Endoscopic swept-source optical coherence tomography based on a two-axis microelectromechanical system mirror

Donglin Wang, Linlai Fu, Xin Wang, Zhongjian Gong*, Sean Samuelson, Can Duan, Hongzhi Jia, Jun Shan Ma, Huikai Xie

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)

Abstract

A microelectromechanical system (MEMS) mirror based endoscopic swept-source optical coherence tomography (SS-OCT) system that can perform three-dimensional (3-D) imaging at high speed is reported. The key component enabling 3-D endoscopic imaging is a two-axis MEMS scanning mirror which has a 0.8 × 0.8 mm2mirror plate and a 1.6 × 1.4 mm 2 device footprint. The diameter of the endoscopic probe is only 3.5 mm. The imaging rate of the SS-OCT system is 50 frames/s. OCT images of both human suspicious oral leukoplakia tissue and normal buccal mucosa were taken in vivo and compared. The OCT imaging result agrees well with the histopathological analysis.

Original languageEnglish
Article number086005
JournalJournal of Biomedical Optics
Volume18
Issue number8
DOIs
Publication statusPublished - Aug 2013
Externally publishedYes

Keywords

  • microelectromechanical system mirror
  • optical coherence tomography
  • oral cancer

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