Emerging Optoelectronic Devices Based on Microscale LEDs and Their Use as Implantable Biomedical Applications

Haijian Zhang, Yanxiu Peng, Nuohan Zhang, Jian Yang, Yongtian Wang, He Ding*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)

Abstract

Thin-film microscale light-emitting diodes (LEDs) are efficient light sources and their integrated applications offer robust capabilities and potential strategies in biomedical science. By leveraging innovations in the design of optoelectronic semiconductor structures, advanced fabrication tech-niques, biocompatible encapsulation, remote control circuits, wireless power supply strategies, etc., these emerging applications provide implantable probes that differ from conventional tethering techniques such as optical fibers. This review introduces the recent advancements of thin-film microscale LEDs for biomedical applications, covering the device lift-off and transfer printing fabrication pro-cesses and the representative biomedical applications for light stimulation, therapy, and photometric biosensing. Wireless power delivery systems have been outlined and discussed to facilitate the operation of implantable probes. With such wireless, battery-free, and minimally invasive implantable light-source probes, these biomedical applications offer excellent opportunities and instruments for both biomedical sciences research and clinical diagnosis and therapy.

Original languageEnglish
Article number1069
JournalMicromachines
Volume13
Issue number7
DOIs
Publication statusPublished - Jul 2022

Keywords

  • lift-off
  • microscale LEDs
  • optogenetics
  • photometry
  • phototherapy
  • transfer printing

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Zhang, H., Peng, Y., Zhang, N., Yang, J., Wang, Y., & Ding, H. (2022). Emerging Optoelectronic Devices Based on Microscale LEDs and Their Use as Implantable Biomedical Applications. Micromachines, 13(7), Article 1069. https://doi.org/10.3390/mi13071069