Efficient Synthesis of 5-Trifluoromethylthio-1,2,3-Triazoles: One-Pot Multicomponent Reaction from Elemental Sulfur and TMSCF 3

Lin Lin Zhang; Meng Tian Li; Liang Liang Shen; Qin Pei Wu

doi:10.1055/s-0039-1690716

Efficient Synthesis of 5-Trifluoromethylthio-1,2,3-Triazoles: One-Pot Multicomponent Reaction from Elemental Sulfur and TMSCF ₃

Lin Lin Zhang, Meng Tian Li, Liang Liang Shen, Qin Pei Wu^*

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

A sequential multistep reaction toward 5-trifluoromethyl thio-1,2,3-triazoles has been established, starting from alkynes, organo azides, S ₈, and (trifluoromethyl)trimethylsilane (TMSCF ₃). This reaction features mild conditions, easy operation, and readily available substrates.

Original language	English
Article number	ss-2019-h0451-op
Pages (from-to)	304-310
Number of pages	7
Journal	Synthesis
Volume	52
Issue number	2
DOIs	https://doi.org/10.1055/s-0039-1690716
Publication status	Published - 2020

Keywords

(trifluoromethyl)trimethylsilane
copper iodide
multicomponent reaction
sulfur
triazole

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10.1055/s-0039-1690716

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title = "Efficient Synthesis of 5-Trifluoromethylthio-1,2,3-Triazoles: One-Pot Multicomponent Reaction from Elemental Sulfur and TMSCF 3",

abstract = "A sequential multistep reaction toward 5-trifluoromethyl thio-1,2,3-triazoles has been established, starting from alkynes, organo azides, S 8, and (trifluoromethyl)trimethylsilane (TMSCF 3). This reaction features mild conditions, easy operation, and readily available substrates.",

keywords = "(trifluoromethyl)trimethylsilane, copper iodide, multicomponent reaction, sulfur, triazole",

author = "Zhang, {Lin Lin} and Li, {Meng Tian} and Shen, {Liang Liang} and Wu, {Qin Pei}",

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pages = "304--310",

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T2 - One-Pot Multicomponent Reaction from Elemental Sulfur and TMSCF 3

AU - Zhang, Lin Lin

AU - Li, Meng Tian

AU - Shen, Liang Liang

AU - Wu, Qin Pei

PY - 2020

Y1 - 2020

N2 - A sequential multistep reaction toward 5-trifluoromethyl thio-1,2,3-triazoles has been established, starting from alkynes, organo azides, S 8, and (trifluoromethyl)trimethylsilane (TMSCF 3). This reaction features mild conditions, easy operation, and readily available substrates.

AB - A sequential multistep reaction toward 5-trifluoromethyl thio-1,2,3-triazoles has been established, starting from alkynes, organo azides, S 8, and (trifluoromethyl)trimethylsilane (TMSCF 3). This reaction features mild conditions, easy operation, and readily available substrates.

KW - (trifluoromethyl)trimethylsilane

KW - copper iodide

KW - multicomponent reaction

KW - sulfur

KW - triazole

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U2 - 10.1055/s-0039-1690716

DO - 10.1055/s-0039-1690716

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JF - Synthesis

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ER -

Efficient Synthesis of 5-Trifluoromethylthio-1,2,3-Triazoles: One-Pot Multicomponent Reaction from Elemental Sulfur and TMSCF ₃

Abstract

Keywords

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