Efficient access to polysubstituted amidines, benzimidazoles and pyrimidines from amides

Jing Wang; Zhenxing He; Xiaopeng Chen; Wangze Song; Ping Lu; Yanguang Wang

doi:10.1016/j.tet.2009.12.034

Efficient access to polysubstituted amidines, benzimidazoles and pyrimidines from amides

Jing Wang, Zhenxing He, Xiaopeng Chen, Wangze Song, Ping Lu^*, Yanguang Wang

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

Polysubstituted amidines, benzimidazoles and pyrimidines were synthesized via the electrophilic activation of amides with trifluoromethanesulfonic anhydride and 2-chloropyridine. The one-pot protocol is concise and efficient and the substrates are readily available.

Original language	English
Pages (from-to)	1208-1214
Number of pages	7
Journal	Tetrahedron
Volume	66
Issue number	6
DOIs	https://doi.org/10.1016/j.tet.2009.12.034
Publication status	Published - 6 Feb 2010
Externally published	Yes

Keywords

Amides
Amidines
Benzimidazoles
Electrophilic activation
Pyrimidines

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10.1016/j.tet.2009.12.034

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title = "Efficient access to polysubstituted amidines, benzimidazoles and pyrimidines from amides",

abstract = "Polysubstituted amidines, benzimidazoles and pyrimidines were synthesized via the electrophilic activation of amides with trifluoromethanesulfonic anhydride and 2-chloropyridine. The one-pot protocol is concise and efficient and the substrates are readily available.",

keywords = "Amides, Amidines, Benzimidazoles, Electrophilic activation, Pyrimidines",

author = "Jing Wang and Zhenxing He and Xiaopeng Chen and Wangze Song and Ping Lu and Yanguang Wang",

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T1 - Efficient access to polysubstituted amidines, benzimidazoles and pyrimidines from amides

AU - Wang, Jing

AU - He, Zhenxing

AU - Chen, Xiaopeng

AU - Song, Wangze

AU - Lu, Ping

AU - Wang, Yanguang

PY - 2010/2/6

Y1 - 2010/2/6

N2 - Polysubstituted amidines, benzimidazoles and pyrimidines were synthesized via the electrophilic activation of amides with trifluoromethanesulfonic anhydride and 2-chloropyridine. The one-pot protocol is concise and efficient and the substrates are readily available.

AB - Polysubstituted amidines, benzimidazoles and pyrimidines were synthesized via the electrophilic activation of amides with trifluoromethanesulfonic anhydride and 2-chloropyridine. The one-pot protocol is concise and efficient and the substrates are readily available.

KW - Amides

KW - Amidines

KW - Benzimidazoles

KW - Electrophilic activation

KW - Pyrimidines

UR - http://www.scopus.com/inward/record.url?scp=73649135364&partnerID=8YFLogxK

U2 - 10.1016/j.tet.2009.12.034

DO - 10.1016/j.tet.2009.12.034

M3 - Article

AN - SCOPUS:73649135364

SN - 0040-4020

VL - 66

SP - 1208

EP - 1214

JO - Tetrahedron

JF - Tetrahedron

IS - 6

ER -

Efficient access to polysubstituted amidines, benzimidazoles and pyrimidines from amides

Abstract

Keywords

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