DNA Sequence Design Based on Template Strategy

Wenbin Liu*, Shudong Wang, Lin Gao, Fengyue Zhang, Jin Xu

*Corresponding author for this work

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Abstract

In DNA based computation and DNA nanotechnology, the design of proper DNA sequences has turned out to be an elementary problem. This paper takes a further look at the template strategy proposed in work by Frutos, A. G. et al. (Nucleic Acids Res. 1997, 25, 4748-4757). The H-measure proposed by Garzon et al. (Proceedings of the Second Annual Genetic Programming Conference, 1997; pp 472-487) is combined in this strategy to optimize the template and map sets obtained. Finally we describe a constructing method that can still produce more sequences by the results obtained in this paper.

Original languageEnglish
Pages (from-to)2014-2018
Number of pages5
JournalJournal of Chemical Information and Computer Sciences
Volume43
Issue number6
DOIs
Publication statusPublished - Nov 2003
Externally publishedYes

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Liu, W., Wang, S., Gao, L., Zhang, F., & Xu, J. (2003). DNA Sequence Design Based on Template Strategy. Journal of Chemical Information and Computer Sciences, 43(6), 2014-2018. https://doi.org/10.1021/ci025645s