Diagnosis potential of near infrared Mueller Matrix imaging for colonic adenocarcinoma

Jianfeng Wang, Wei Zheng, Kan Lin, Zhiwei Huang*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Mueller matrix imaging along with polar decomposition method was employed for the colonic adenocarcinoma detection by polarized light in the near-infrared spectral range (700-1100 nm). A high-speed (<5s) Muller matrix imaging system with dual-rotating waveplates was developed. 16 (4 by 4) full Mueller matrices of the colonic tissues (i.e., normal and caner) were acquired. Polar decomposition was further implemented on the 16 images to derive the diattentuation, depolarization, and the retardance images. The decomposed images showed clear margin between the normal and adenocarcinomaous colon tissue samples. The work shows the potential of near-infrared Mueller matrix imaging for the early diagnosis and detection of malignant lesions in the colon.

Original languageEnglish
Title of host publicationAdvanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV
EditorsTuan Vo-Dinh, Anita Mahadevan-Jansen, Warren S. Grundfest
PublisherSPIE
ISBN (Electronic)9781628419320
DOIs
Publication statusPublished - 2016
Externally publishedYes
EventAdvanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV - San Francisco, United States
Duration: 14 Feb 201616 Feb 2016

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9698
ISSN (Print)1605-7422

Conference

ConferenceAdvanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV
Country/TerritoryUnited States
CitySan Francisco
Period14/02/1616/02/16

Keywords

  • Colonic Adenocarcinoma
  • Mueller Matrix Imaging

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