Detection system for singlet oxygen luminescence in photodynamic therapy

Buhong Li; Huiyun Lin; Defu Chen; Min Wang; Shusen Xie

doi:10.3788/COL20100801.0086

Detection system for singlet oxygen luminescence in photodynamic therapy

Buhong Li^*, Huiyun Lin, Defu Chen, Min Wang, Shusen Xie

^*Corresponding author for this work

Fujian Normal University

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Singlet oxygen (¹O₂) is widely considered to play a major role in photodynamic therapy (PDT), and thus an increasing attention has been focused on the direct detection of ¹O₂ near-infrared luminescence around 1270 nm for PDT dosimetry. A new sensitive detection system is developed to directly measure the temporal and spectral resolved ¹O₂ luminescence spectra. The triplet state and ¹O₂ lifetimes of Rose Bengal as a model photosensitizer in different solvents are determined, and the obtained results agree well with the published data. Our detection system has the potential application in ¹O₂ luminescence-based PDT dosimetry.

Original language	English
Pages (from-to)	86-88
Number of pages	3
Journal	Chinese Optics Letters
Volume	8
Issue number	1
DOIs	https://doi.org/10.3788/COL20100801.0086
Publication status	Published - Jan 2010
Externally published	Yes

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title = "Detection system for singlet oxygen luminescence in photodynamic therapy",

abstract = "Singlet oxygen (1O2) is widely considered to play a major role in photodynamic therapy (PDT), and thus an increasing attention has been focused on the direct detection of 1O2 near-infrared luminescence around 1270 nm for PDT dosimetry. A new sensitive detection system is developed to directly measure the temporal and spectral resolved 1O2 luminescence spectra. The triplet state and 1O2 lifetimes of Rose Bengal as a model photosensitizer in different solvents are determined, and the obtained results agree well with the published data. Our detection system has the potential application in 1O2 luminescence-based PDT dosimetry.",

author = "Buhong Li and Huiyun Lin and Defu Chen and Min Wang and Shusen Xie",

year = "2010",

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AU - Li, Buhong

AU - Lin, Huiyun

AU - Chen, Defu

AU - Wang, Min

AU - Xie, Shusen

PY - 2010/1

Y1 - 2010/1

N2 - Singlet oxygen (1O2) is widely considered to play a major role in photodynamic therapy (PDT), and thus an increasing attention has been focused on the direct detection of 1O2 near-infrared luminescence around 1270 nm for PDT dosimetry. A new sensitive detection system is developed to directly measure the temporal and spectral resolved 1O2 luminescence spectra. The triplet state and 1O2 lifetimes of Rose Bengal as a model photosensitizer in different solvents are determined, and the obtained results agree well with the published data. Our detection system has the potential application in 1O2 luminescence-based PDT dosimetry.

AB - Singlet oxygen (1O2) is widely considered to play a major role in photodynamic therapy (PDT), and thus an increasing attention has been focused on the direct detection of 1O2 near-infrared luminescence around 1270 nm for PDT dosimetry. A new sensitive detection system is developed to directly measure the temporal and spectral resolved 1O2 luminescence spectra. The triplet state and 1O2 lifetimes of Rose Bengal as a model photosensitizer in different solvents are determined, and the obtained results agree well with the published data. Our detection system has the potential application in 1O2 luminescence-based PDT dosimetry.

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JO - Chinese Optics Letters

JF - Chinese Optics Letters

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Detection system for singlet oxygen luminescence in photodynamic therapy

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