Design of integrated control system for microfluidic PCR analysis instrument

Jiandong Xu*, Xuefei Lv, Yun Liu, Xiaoqiong Li, Yulin Deng

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Citations (Scopus)

Abstract

In this study, the design and development of an integrated control system for microfluidic PCR analysis instrument was presented. PID temperature control algorithm is used. The micro pumps, micro valves, and micro-mixers are command controlled by PC serial port to work together for samples and reagents driving. Sequential control strategy is introduced to control micro-pumps, micro valves, mixers, high-voltage module, and PCR reaction temperature. Labview as a software development platform is utilized to achieve human-computer exchange. All these designs are aimed to achieve the PCR reaction continuously on line from DNA extraction, purification, amplification to detection. An effective design idea for the coupling of complex microfluidic chip and instrument control was providing.

Original languageEnglish
Title of host publicationIndustrial Instrumentation and Control Systems
Pages1491-1495
Number of pages5
DOIs
Publication statusPublished - 2013
Event2012 International Conference on Measurement, Instrumentation and Automation, ICMIA 2012 - Guangzhou, China
Duration: 15 Sept 201216 Sept 2012

Publication series

NameApplied Mechanics and Materials
Volume241-244
ISSN (Print)1660-9336
ISSN (Electronic)1662-7482

Conference

Conference2012 International Conference on Measurement, Instrumentation and Automation, ICMIA 2012
Country/TerritoryChina
CityGuangzhou
Period15/09/1216/09/12

Keywords

  • Integrated control system
  • Microfluidic chip
  • PCR

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