Changes of the Local Brain Network Property Regions in Alzheimer's Disease Based on Graph Theory

Bing Zhu*, Qi Li, Chunjie Guo, Yu Yang, Jinglong Wu, Zhilin Zhang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Alzheimer's disease (AD) is an irreversible degenerative disease of the nervous system. Early diagnosis of Alzheimer's disease is the key to treatment. This study adopted clinical neuropsychological examinations and functional Magnetic Resonance Imaging brain network properties constructed by graph theory. The results of clinical neuropsychological examinations and five local network topological properties with significant differences among the AD, Mild Cognitive Impairment and normal control groups were analyzed. Twenty-seven local brain network property regions were extracted in the anatomical automatic marking (AAL) 90 template. In short, the changes in local brain network property regions can be used as important markers to distinguish AD patients. It also plays a reference effect on AD's early diagnosis.

Original languageEnglish
Title of host publication2022 16th ICME International Conference on Complex Medical Engineering, CME 2022
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages151-155
Number of pages5
ISBN (Electronic)9781665496995
DOIs
Publication statusPublished - 2022
Externally publishedYes
Event16th ICME International Conference on Complex Medical Engineering, CME 2022 - Virtual, Online, China
Duration: 4 Nov 20226 Nov 2022

Publication series

Name2022 16th ICME International Conference on Complex Medical Engineering, CME 2022

Conference

Conference16th ICME International Conference on Complex Medical Engineering, CME 2022
Country/TerritoryChina
CityVirtual, Online
Period4/11/226/11/22

Keywords

  • Alzheimer's disease
  • brain network
  • clinical neuropsychological examination
  • functional Magnetic Resonance Imaging
  • graph theory

Fingerprint

Dive into the research topics of 'Changes of the Local Brain Network Property Regions in Alzheimer's Disease Based on Graph Theory'. Together they form a unique fingerprint.

Cite this