CeCl3·7H2O as an efficient catalyst for one-pot synthesis of β-amino ketones by three-component Mannich reaction

Yan Dai; Bin Dong Li; Heng Dao Quan; Chun Xu Lü

doi:10.1016/j.cclet.2009.08.011

CeCl₃·7H₂O as an efficient catalyst for one-pot synthesis of β-amino ketones by three-component Mannich reaction

Yan Dai, Bin Dong Li, Heng Dao Quan, Chun Xu Lü^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

Cerium trichloride heptahydrate (CeCl₃·7H₂O) was found to be an efficient and recyclable catalyst for the three-component direct Mannich reaction of anilines and benzaldehydes with acetophenone. This protocol has advantages of high yield, no environmental pollution, mild condition, and simple work-up procedure.

Original language	English
Pages (from-to)	31-34
Number of pages	4
Journal	Chinese Chemical Letters
Volume	21
Issue number	1
DOIs	https://doi.org/10.1016/j.cclet.2009.08.011
Publication status	Published - Jan 2010
Externally published	Yes

Keywords

Cerium trichloride heptahydrate
Lewis acid
Mannich reaction
β-Amino ketones

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.cclet.2009.08.011

Cite this

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title = "CeCl3·7H2O as an efficient catalyst for one-pot synthesis of β-amino ketones by three-component Mannich reaction",

abstract = "Cerium trichloride heptahydrate (CeCl3·7H2O) was found to be an efficient and recyclable catalyst for the three-component direct Mannich reaction of anilines and benzaldehydes with acetophenone. This protocol has advantages of high yield, no environmental pollution, mild condition, and simple work-up procedure.",

keywords = "Cerium trichloride heptahydrate, Lewis acid, Mannich reaction, β-Amino ketones",

author = "Yan Dai and Li, {Bin Dong} and Quan, {Heng Dao} and L{\"u}, {Chun Xu}",

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AU - Dai, Yan

AU - Li, Bin Dong

AU - Quan, Heng Dao

AU - Lü, Chun Xu

PY - 2010/1

Y1 - 2010/1

N2 - Cerium trichloride heptahydrate (CeCl3·7H2O) was found to be an efficient and recyclable catalyst for the three-component direct Mannich reaction of anilines and benzaldehydes with acetophenone. This protocol has advantages of high yield, no environmental pollution, mild condition, and simple work-up procedure.

AB - Cerium trichloride heptahydrate (CeCl3·7H2O) was found to be an efficient and recyclable catalyst for the three-component direct Mannich reaction of anilines and benzaldehydes with acetophenone. This protocol has advantages of high yield, no environmental pollution, mild condition, and simple work-up procedure.

KW - Cerium trichloride heptahydrate

KW - Lewis acid

KW - Mannich reaction

KW - β-Amino ketones

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DO - 10.1016/j.cclet.2009.08.011

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