TY - JOUR
T1 - Application of Submicron Electrospray Emitter in Native Mass Spectrometry Analysis
AU - Zhang, Yu
AU - Tang, Yang
AU - Xu, Wei
N1 - Publisher Copyright:
© 2021, China Association for Instrumental Analysis. All rights reserved.
PY - 2021
Y1 - 2021
N2 - Native mass spectrometry has become one of the important tools for characterizing protein structures. Compared with traditional electrospray emitter (ESI emitter) , submicron electrospray emitters have various characteristics such as changing the charge-state distribution of ions and ion de- salting, which could be directly used to analyze the protein structures in the physiological environ- ment. In this review, the characteristics and applications of submicron electrospray emitters in native mass spectrometry analysis are discussed and summarized, and their future developments are also en- visioned.
AB - Native mass spectrometry has become one of the important tools for characterizing protein structures. Compared with traditional electrospray emitter (ESI emitter) , submicron electrospray emitters have various characteristics such as changing the charge-state distribution of ions and ion de- salting, which could be directly used to analyze the protein structures in the physiological environ- ment. In this review, the characteristics and applications of submicron electrospray emitters in native mass spectrometry analysis are discussed and summarized, and their future developments are also en- visioned.
KW - charge-state distribution
KW - ion desalting
KW - native mass spectrometry
KW - submicron electrospray emitters
UR - http://www.scopus.com/inward/record.url?scp=85142174798&partnerID=8YFLogxK
U2 - 10.3969/j.issn.1004-4957.2021.02.009
DO - 10.3969/j.issn.1004-4957.2021.02.009
M3 - Article
AN - SCOPUS:85142174798
SN - 1004-4957
VL - 40
SP - 227
EP - 231
JO - Journal of Instrumental Analysis
JF - Journal of Instrumental Analysis
IS - 2
ER -