Analytical reconstruction of quantitative SPECT with parallel geometry

Hong Bing Lu*, Zhengrong J. Liang, Junhai Wen, Gang Li, Xin Liu, Shu Yi Wang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Based on Kunyansky's and our previous work, an efficient, analytical solution to the reconstruction problem of myocardial perfusion SPECT has been developed that allows simultaneous compensation for non-uniform attenuation, scatter, and system-dependent resolution variation, as well as suppression of signal-dependent Poisson noise. The preliminary digital and Monte Carlo simulation results using a realistic human thoracic phantom demonstrate that, for parallel-beam geometry, the proposed analytical reconstruction scheme is computationally comparable to filtered backprojection and quantitatively equivalent to iterative maximum a posteriori expectation-maximization reconstruction.

Original languageEnglish
Pages (from-to)524-530
Number of pages7
JournalChinese Journal of Biomedical Engineering
Volume24
Issue number5
Publication statusPublished - Oct 2005
Externally publishedYes

Keywords

  • Analytical algorithm
  • Degradation factors
  • Parallel-beam
  • Quantitative reconstruction
  • SPECT

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