Advances of Microfluidic Technologies Applied in Bio-analytical Chemistry

Feng ZHANG, Dan GAO*, Qiong Lin LIANG

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

14 Citations (Scopus)

Abstract

Compared with conventional analysis system, microfluidics-based analysis system has many advantages, such as low consumption of sample and reagent, high efficiency in mass and heat transfer, good biocompatibility, high-throughput parallel analysis, as well as its integration, miniaturization and automation. It has been widely applied in the analytical chemistry, especially in the field of bio-analytical chemistry. In this review, we mainly focused on the progress of microfluidic technologies for cellular application during the past five years, such as the chip material and fabrication, surface modification and droplet techniques. Then we briefly summarized the applications of microfluidic techniques in drug screening and cellular analysis.

Original languageEnglish
Pages (from-to)1942-1949
Number of pages8
JournalChinese Journal of Analytical Chemistry
Volume44
Issue number12
DOIs
Publication statusPublished - Dec 2016
Externally publishedYes

Keywords

  • Cell analysis
  • Drug screening
  • Microfluidic technology
  • Review

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