Abstract
Aptamer is a kind of synthetic oligonucleotides discriminated by in vitro screening, which is of high affinity and specificity with its ligands. Some new methods for efficient and fast detection for biochemical and biomedical purposes are being developed based on the molecular recognition of aptamers. In this paper, recent advance in the screening, chemical modification of aptamers and their applications in analytical chemistry and enzyme chemistry are reviewed.
Original language | English |
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Pages (from-to) | 1026-1033 |
Number of pages | 8 |
Journal | Progress in Chemistry |
Volume | 19 |
Issue number | 6 |
Publication status | Published - Jun 2007 |
Keywords
- Aptamers
- Modification
- SELEX
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Xie, H., Chen, X., & Deng, Y. (2007). Advance in aptamer research. Progress in Chemistry, 19(6), 1026-1033.