Advance in aptamer research

Haiyan Xie*, Xuechai Chen, Yulin Deng

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Aptamer is a kind of synthetic oligonucleotides discriminated by in vitro screening, which is of high affinity and specificity with its ligands. Some new methods for efficient and fast detection for biochemical and biomedical purposes are being developed based on the molecular recognition of aptamers. In this paper, recent advance in the screening, chemical modification of aptamers and their applications in analytical chemistry and enzyme chemistry are reviewed.

Original languageEnglish
Pages (from-to)1026-1033
Number of pages8
JournalProgress in Chemistry
Volume19
Issue number6
Publication statusPublished - Jun 2007

Keywords

  • Aptamers
  • Modification
  • SELEX

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Xie, H., Chen, X., & Deng, Y. (2007). Advance in aptamer research. Progress in Chemistry, 19(6), 1026-1033.