TY - JOUR
T1 - Acoustohydrodynamic micromixers
T2 - Basic mixing principles, programmable mixing prospectives, and biomedical applications
AU - Bai, Chenhao
AU - Tang, Xiaoqing
AU - Li, Yuyang
AU - Arai, Tatsuo
AU - Huang, Qiang
AU - Liu, Xiaoming
N1 - Publisher Copyright:
© 2024 Author(s).
PY - 2024/3/1
Y1 - 2024/3/1
N2 - Acoustohydrodynamic micromixers offer excellent mixing efficiency, cost-effectiveness, and flexible controllability compared with conventional micromixers. There are two mechanisms in acoustic micromixers: indirect influence by induced streamlines, exemplified by sharp-edge micromixers, and direct influence by acoustic waves, represented by surface acoustic wave micromixers. The former utilizes sharp-edge structures, while the latter employs acoustic wave action to affect both the fluid and its particles. However, traditional micromixers with acoustic bubbles achieve significant mixing performance and numerous programmable mixing platforms provide excellent solutions with wide applicability. This review offers a comprehensive overview of various micromixers, elucidates their underlying principles, and explores their biomedical applications. In addition, advanced programmable micromixing with impressive versatility, convenience, and ability of cross-scale operations is introduced in detail. We believe this review will benefit the researchers in the biomedical field to know the micromixers and find a suitable micromixing method for their various applications.
AB - Acoustohydrodynamic micromixers offer excellent mixing efficiency, cost-effectiveness, and flexible controllability compared with conventional micromixers. There are two mechanisms in acoustic micromixers: indirect influence by induced streamlines, exemplified by sharp-edge micromixers, and direct influence by acoustic waves, represented by surface acoustic wave micromixers. The former utilizes sharp-edge structures, while the latter employs acoustic wave action to affect both the fluid and its particles. However, traditional micromixers with acoustic bubbles achieve significant mixing performance and numerous programmable mixing platforms provide excellent solutions with wide applicability. This review offers a comprehensive overview of various micromixers, elucidates their underlying principles, and explores their biomedical applications. In addition, advanced programmable micromixing with impressive versatility, convenience, and ability of cross-scale operations is introduced in detail. We believe this review will benefit the researchers in the biomedical field to know the micromixers and find a suitable micromixing method for their various applications.
UR - http://www.scopus.com/inward/record.url?scp=85191376793&partnerID=8YFLogxK
U2 - 10.1063/5.0179750
DO - 10.1063/5.0179750
M3 - Article
AN - SCOPUS:85191376793
SN - 1932-1058
VL - 18
JO - Biomicrofluidics
JF - Biomicrofluidics
IS - 2
ER -