A thermally switchable chromatographic material for selective capture and rapid release of proteins and nucleotides

Zongjian Liu; Rui Su; Xiao Liang; Yanli Liang; Yulin Deng; Yujuan Li; Rongji Dai

doi:10.1039/c3ra41454j

A thermally switchable chromatographic material for selective capture and rapid release of proteins and nucleotides

Zongjian Liu, Rui Su, Xiao Liang, Yanli Liang, Yulin Deng^*, Yujuan Li, Rongji Dai

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

We report a switchable chromatographic material for the selective capture-release of proteins with simpler adjustment of the temperature instead of the conventional need to change the mobile phase. This novel strategy greatly increased the number of LC/MS/MS-identified proteins from human serum, as well as their scores and coverage ratios. This journal is

Original language	English
Pages (from-to)	15830-15834
Number of pages	5
Journal	RSC Advances
Volume	4
Issue number	31
DOIs	https://doi.org/10.1039/c3ra41454j
Publication status	Published - 2014

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10.1039/c3ra41454j

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abstract = "We report a switchable chromatographic material for the selective capture-release of proteins with simpler adjustment of the temperature instead of the conventional need to change the mobile phase. This novel strategy greatly increased the number of LC/MS/MS-identified proteins from human serum, as well as their scores and coverage ratios. This journal is",

author = "Zongjian Liu and Rui Su and Xiao Liang and Yanli Liang and Yulin Deng and Yujuan Li and Rongji Dai",

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T1 - A thermally switchable chromatographic material for selective capture and rapid release of proteins and nucleotides

AU - Liu, Zongjian

AU - Su, Rui

AU - Liang, Xiao

AU - Liang, Yanli

AU - Deng, Yulin

AU - Li, Yujuan

AU - Dai, Rongji

PY - 2014

Y1 - 2014

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AB - We report a switchable chromatographic material for the selective capture-release of proteins with simpler adjustment of the temperature instead of the conventional need to change the mobile phase. This novel strategy greatly increased the number of LC/MS/MS-identified proteins from human serum, as well as their scores and coverage ratios. This journal is

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U2 - 10.1039/c3ra41454j

DO - 10.1039/c3ra41454j

M3 - Article

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VL - 4

SP - 15830

EP - 15834

JO - RSC Advances

JF - RSC Advances

IS - 31

ER -

A thermally switchable chromatographic material for selective capture and rapid release of proteins and nucleotides

Abstract

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