A Review on Microfluidic Platforms Applied to Nerve Regeneration

Chuankai Dai; Xiaoming Liu; Rongyu Tang; Jiping He; Tatsuo Arai

doi:10.3390/app12073534

A Review on Microfluidic Platforms Applied to Nerve Regeneration

Chuankai Dai, Xiaoming Liu^*, Rongyu Tang, Jiping He, Tatsuo Arai

^*Corresponding author for this work

School of Mechatronical Engineering

Research output: Contribution to journal › Review article › peer-review

6 Citations (Scopus)

Abstract

In recent decades, microfluidics have significantly advanced nerve regeneration research. Microfluidic devices can provide an accurate simulation of in vivo microenvironment for different research purposes such as analyzing myelin growth inhibitory factors, screening drugs, assessing nerve growth factors, and exploring mechanisms of neural injury and regeneration. The microfluidic platform offers technical supports for nerve regeneration that enable precise spatio-temporal control of cells, such as neuron isolation, single-cell manipulation, neural patterning, and axon guidance. In this paper, we review the development and recent advances of microfluidic platforms for nerve regeneration research.

Original language	English
Article number	3534
Journal	Applied Sciences (Switzerland)
Volume	12
Issue number	7
DOIs	https://doi.org/10.3390/app12073534
Publication status	Published - 1 Apr 2022

Keywords

axon guidance
axon regrowth
microfluidic device
nerve regeneration
nerve repair
neurite outgrowth

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title = "A Review on Microfluidic Platforms Applied to Nerve Regeneration",

abstract = "In recent decades, microfluidics have significantly advanced nerve regeneration research. Microfluidic devices can provide an accurate simulation of in vivo microenvironment for different research purposes such as analyzing myelin growth inhibitory factors, screening drugs, assessing nerve growth factors, and exploring mechanisms of neural injury and regeneration. The microfluidic platform offers technical supports for nerve regeneration that enable precise spatio-temporal control of cells, such as neuron isolation, single-cell manipulation, neural patterning, and axon guidance. In this paper, we review the development and recent advances of microfluidic platforms for nerve regeneration research.",

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author = "Chuankai Dai and Xiaoming Liu and Rongyu Tang and Jiping He and Tatsuo Arai",

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T1 - A Review on Microfluidic Platforms Applied to Nerve Regeneration

AU - Dai, Chuankai

AU - Liu, Xiaoming

AU - Tang, Rongyu

AU - He, Jiping

AU - Arai, Tatsuo

PY - 2022/4/1

Y1 - 2022/4/1

N2 - In recent decades, microfluidics have significantly advanced nerve regeneration research. Microfluidic devices can provide an accurate simulation of in vivo microenvironment for different research purposes such as analyzing myelin growth inhibitory factors, screening drugs, assessing nerve growth factors, and exploring mechanisms of neural injury and regeneration. The microfluidic platform offers technical supports for nerve regeneration that enable precise spatio-temporal control of cells, such as neuron isolation, single-cell manipulation, neural patterning, and axon guidance. In this paper, we review the development and recent advances of microfluidic platforms for nerve regeneration research.

AB - In recent decades, microfluidics have significantly advanced nerve regeneration research. Microfluidic devices can provide an accurate simulation of in vivo microenvironment for different research purposes such as analyzing myelin growth inhibitory factors, screening drugs, assessing nerve growth factors, and exploring mechanisms of neural injury and regeneration. The microfluidic platform offers technical supports for nerve regeneration that enable precise spatio-temporal control of cells, such as neuron isolation, single-cell manipulation, neural patterning, and axon guidance. In this paper, we review the development and recent advances of microfluidic platforms for nerve regeneration research.

KW - axon guidance

KW - axon regrowth

KW - microfluidic device

KW - nerve regeneration

KW - nerve repair

KW - neurite outgrowth

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DO - 10.3390/app12073534

M3 - Review article

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SN - 2076-3417

VL - 12

JO - Applied Sciences (Switzerland)

JF - Applied Sciences (Switzerland)

IS - 7

M1 - 3534

ER -

A Review on Microfluidic Platforms Applied to Nerve Regeneration

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Keywords

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