A Novel Lactam Metabolite from Penicillium sclerotium D35

T. Liu; C. L. Gong; J. Zhao; D. Dan; T. T. Zhang; L. L. Gao; Q. Zhang

doi:10.1007/s10600-021-03378-y

A Novel Lactam Metabolite from Penicillium sclerotium D35

T. Liu, C. L. Gong, J. Zhao, D. Dan, T. T. Zhang, L. L. Gao^*, Q. Zhang^*

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

A novel lactam metabolite, 1-pentyl-8-oxa-3,6-diazabicyclo[3.2.1]octane-2,4,7-trione (1), was isolated from Penicillium sclerotium D35. The structure of the new compound 1 was elucidated by spectroscopic methods, including 1D and 2D NMR data and HR-MS. Compound 1 showed moderate nematode suppression activity with LC₅₀ values of 344.722 mg/L.

Original language	English
Pages (from-to)	420-421
Number of pages	2
Journal	Chemistry of Natural Compounds
Volume	57
Issue number	3
DOIs	https://doi.org/10.1007/s10600-021-03378-y
Publication status	Published - May 2021

Keywords

Penicillium sclerotium D35
lactam metabolite
nematocidal activity

Access to Document

10.1007/s10600-021-03378-y

Cite this

@article{cc5813a847e94c87a30e1a90f3ae7939,

title = "A Novel Lactam Metabolite from Penicillium sclerotium D35",

abstract = "A novel lactam metabolite, 1-pentyl-8-oxa-3,6-diazabicyclo[3.2.1]octane-2,4,7-trione (1), was isolated from Penicillium sclerotium D35. The structure of the new compound 1 was elucidated by spectroscopic methods, including 1D and 2D NMR data and HR-MS. Compound 1 showed moderate nematode suppression activity with LC50 values of 344.722 mg/L.",

keywords = "Penicillium sclerotium D35, lactam metabolite, nematocidal activity",

author = "T. Liu and Gong, {C. L.} and J. Zhao and D. Dan and Zhang, {T. T.} and Gao, {L. L.} and Q. Zhang",

note = "Publisher Copyright: {\textcopyright} 2021, Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2021",

month = may,

doi = "10.1007/s10600-021-03378-y",

language = "English",

volume = "57",

pages = "420--421",

journal = "Chemistry of Natural Compounds",

issn = "0009-3130",

publisher = "Springer New York",

number = "3",

}

TY - JOUR

T1 - A Novel Lactam Metabolite from Penicillium sclerotium D35

AU - Liu, T.

AU - Gong, C. L.

AU - Zhao, J.

AU - Dan, D.

AU - Zhang, T. T.

AU - Gao, L. L.

AU - Zhang, Q.

PY - 2021/5

Y1 - 2021/5

N2 - A novel lactam metabolite, 1-pentyl-8-oxa-3,6-diazabicyclo[3.2.1]octane-2,4,7-trione (1), was isolated from Penicillium sclerotium D35. The structure of the new compound 1 was elucidated by spectroscopic methods, including 1D and 2D NMR data and HR-MS. Compound 1 showed moderate nematode suppression activity with LC50 values of 344.722 mg/L.

AB - A novel lactam metabolite, 1-pentyl-8-oxa-3,6-diazabicyclo[3.2.1]octane-2,4,7-trione (1), was isolated from Penicillium sclerotium D35. The structure of the new compound 1 was elucidated by spectroscopic methods, including 1D and 2D NMR data and HR-MS. Compound 1 showed moderate nematode suppression activity with LC50 values of 344.722 mg/L.

KW - Penicillium sclerotium D35

KW - lactam metabolite

KW - nematocidal activity

UR - http://www.scopus.com/inward/record.url?scp=85106532242&partnerID=8YFLogxK

U2 - 10.1007/s10600-021-03378-y

DO - 10.1007/s10600-021-03378-y

M3 - Article

AN - SCOPUS:85106532242

SN - 0009-3130

VL - 57

SP - 420

EP - 421

JO - Chemistry of Natural Compounds

JF - Chemistry of Natural Compounds

IS - 3

ER -

A Novel Lactam Metabolite from Penicillium sclerotium D35

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this