A Novel Lactam Metabolite from Penicillium sclerotium D35

T. Liu; C. L. Gong; J. Zhao; D. Dan; T. T. Zhang; L. L. Gao; Q. Zhang

doi:10.1007/s10600-021-03378-y

A Novel Lactam Metabolite from Penicillium sclerotium D35

T. Liu, C. L. Gong, J. Zhao, D. Dan, T. T. Zhang, L. L. Gao^*, Q. Zhang^*

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

A novel lactam metabolite, 1-pentyl-8-oxa-3,6-diazabicyclo[3.2.1]octane-2,4,7-trione (1), was isolated from Penicillium sclerotium D35. The structure of the new compound 1 was elucidated by spectroscopic methods, including 1D and 2D NMR data and HR-MS. Compound 1 showed moderate nematode suppression activity with LC₅₀ values of 344.722 mg/L.

Original language	English
Pages (from-to)	420-421
Number of pages	2
Journal	Chemistry of Natural Compounds
Volume	57
Issue number	3
DOIs	https://doi.org/10.1007/s10600-021-03378-y
Publication status	Published - May 2021

Keywords

Penicillium sclerotium D35
lactam metabolite
nematocidal activity

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10.1007/s10600-021-03378-y

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title = "A Novel Lactam Metabolite from Penicillium sclerotium D35",

abstract = "A novel lactam metabolite, 1-pentyl-8-oxa-3,6-diazabicyclo[3.2.1]octane-2,4,7-trione (1), was isolated from Penicillium sclerotium D35. The structure of the new compound 1 was elucidated by spectroscopic methods, including 1D and 2D NMR data and HR-MS. Compound 1 showed moderate nematode suppression activity with LC50 values of 344.722 mg/L.",

keywords = "Penicillium sclerotium D35, lactam metabolite, nematocidal activity",

author = "T. Liu and Gong, {C. L.} and J. Zhao and D. Dan and Zhang, {T. T.} and Gao, {L. L.} and Q. Zhang",

note = "Publisher Copyright: {\textcopyright} 2021, Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2021",

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doi = "10.1007/s10600-021-03378-y",

language = "English",

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T1 - A Novel Lactam Metabolite from Penicillium sclerotium D35

AU - Liu, T.

AU - Gong, C. L.

AU - Zhao, J.

AU - Dan, D.

AU - Zhang, T. T.

AU - Gao, L. L.

AU - Zhang, Q.

PY - 2021/5

Y1 - 2021/5

N2 - A novel lactam metabolite, 1-pentyl-8-oxa-3,6-diazabicyclo[3.2.1]octane-2,4,7-trione (1), was isolated from Penicillium sclerotium D35. The structure of the new compound 1 was elucidated by spectroscopic methods, including 1D and 2D NMR data and HR-MS. Compound 1 showed moderate nematode suppression activity with LC50 values of 344.722 mg/L.

AB - A novel lactam metabolite, 1-pentyl-8-oxa-3,6-diazabicyclo[3.2.1]octane-2,4,7-trione (1), was isolated from Penicillium sclerotium D35. The structure of the new compound 1 was elucidated by spectroscopic methods, including 1D and 2D NMR data and HR-MS. Compound 1 showed moderate nematode suppression activity with LC50 values of 344.722 mg/L.

KW - Penicillium sclerotium D35

KW - lactam metabolite

KW - nematocidal activity

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U2 - 10.1007/s10600-021-03378-y

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SP - 420

EP - 421

JO - Chemistry of Natural Compounds

JF - Chemistry of Natural Compounds

IS - 3

ER -

A Novel Lactam Metabolite from Penicillium sclerotium D35

Abstract

Keywords

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