A new and facile synthesis of quinazoline-2,4(1 H,3H)-diones

Li Jiarong; Chen Xian; Shi Daxin; Ma Shuling; Li Qing; Zhang Qi; Tang Jianhong

doi:10.1021/ol900093h

A new and facile synthesis of quinazoline-2,4(1 H,3H)-diones

Li Jiarong, Chen Xian, Shi Daxin, Ma Shuling^*, Li Qing, Zhang Qi, Tang Jianhong

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

94 Citations (Scopus)

Abstract

A new and facile preparation of quinazoline-2,4(1H,3H)-diones was first reported which was the condensation of aromatic o-aminonitriles with DMF or N,N-diethylformamide in the presence of ZnCl₂ (0.5-10 mol %) at 190-200 °C in the sealed reactor.

Original language	English
Pages (from-to)	1193-1196
Number of pages	4
Journal	Organic Letters
Volume	11
Issue number	6
DOIs	https://doi.org/10.1021/ol900093h
Publication status	Published - 19 Mar 2009

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10.1021/ol900093h

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title = "A new and facile synthesis of quinazoline-2,4(1 H,3H)-diones",

abstract = "A new and facile preparation of quinazoline-2,4(1H,3H)-diones was first reported which was the condensation of aromatic o-aminonitriles with DMF or N,N-diethylformamide in the presence of ZnCl2 (0.5-10 mol %) at 190-200 °C in the sealed reactor.",

author = "Li Jiarong and Chen Xian and Shi Daxin and Ma Shuling and Li Qing and Zhang Qi and Tang Jianhong",

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AU - Jiarong, Li

AU - Xian, Chen

AU - Daxin, Shi

AU - Shuling, Ma

AU - Qing, Li

AU - Qi, Zhang

AU - Jianhong, Tang

PY - 2009/3/19

Y1 - 2009/3/19

N2 - A new and facile preparation of quinazoline-2,4(1H,3H)-diones was first reported which was the condensation of aromatic o-aminonitriles with DMF or N,N-diethylformamide in the presence of ZnCl2 (0.5-10 mol %) at 190-200 °C in the sealed reactor.

AB - A new and facile preparation of quinazoline-2,4(1H,3H)-diones was first reported which was the condensation of aromatic o-aminonitriles with DMF or N,N-diethylformamide in the presence of ZnCl2 (0.5-10 mol %) at 190-200 °C in the sealed reactor.

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A new and facile synthesis of quinazoline-2,4(1 H,3H)-diones

Abstract

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