A high efficient fluidic microchannel for cell immobilization with controllable quantity

Tang Xiaoqing*, Liu Xiaoming, Li Pengyun, Lin Yuqing, Masaru Kojima, Huang Qiang, Tatsuo Arai

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Cell immobilization is an essential process in the cell analysis, cell measurement and cell surgery. Single-cell analysis and multi-cell communication impose different requirements on the number of cells which need immobilized. Advances in microchannel provide us a great tool in cell immobilization, since the applied harmless fluidic field force and controllable closed fluidic environment. In this paper, we propose a high efficient microchannel for trapping cells with controllable quantity, which uses the passive fluidic force and is based on “least flow resistance path” principle. With this presented microchannel design, immobilization of single cell and dual cells have been achieved with success rates of 96% and 95% respectively. Therefore, we expect that the high efficient microchannel can be of great importance for the biological research.

Original languageEnglish
Title of host publication22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PublisherChemical and Biological Microsystems Society
Pages452-454
Number of pages3
ISBN (Electronic)9781510897571
Publication statusPublished - 2018
Event22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 - Kaohsiung, Taiwan, Province of China
Duration: 11 Nov 201815 Nov 2018

Publication series

Name22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Volume1

Conference

Conference22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Country/TerritoryTaiwan, Province of China
CityKaohsiung
Period11/11/1815/11/18

Keywords

  • Controllable quantity
  • Efficient microchannel
  • Immobilization

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