A divergent synthesis of 1,8-naphthyridines and hydropyridopyrimidinones by the reactions of o-aminonitriles with ketones

Liupan Yang; Jiarong Li; Hongxin Chai; Hongyan Lu; Qi Zhang; Daxin Shi

doi:10.1002/cjoc.201201247

A divergent synthesis of 1,8-naphthyridines and hydropyridopyrimidinones by the reactions of o-aminonitriles with ketones

Liupan Yang, Jiarong Li, Hongxin Chai, Hongyan Lu, Qi Zhang, Daxin Shi^*

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

An efficient divergent synthesis of substituted 1,8-naphthyridine and hydropyridopyrimidinone derivatives was developed by the reactions of o-aminocyanopyridines and ketones based on different catalytic conditions. Catalyst-controlled cyclization pathways for the divergent synthesis of 1,8-naphthyridines and hydropyridopyrimidinone derivatives has been developed.

Original language	English
Pages (from-to)	443-448
Number of pages	6
Journal	Chinese Journal of Chemistry
Volume	31
Issue number	4
DOIs	https://doi.org/10.1002/cjoc.201201247
Publication status	Published - Apr 2013

Keywords

1,8-naphthyridine
Friedländer annulations
divergent synthesis
hydropyridopyrimidinone

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10.1002/cjoc.201201247

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abstract = "An efficient divergent synthesis of substituted 1,8-naphthyridine and hydropyridopyrimidinone derivatives was developed by the reactions of o-aminocyanopyridines and ketones based on different catalytic conditions. Catalyst-controlled cyclization pathways for the divergent synthesis of 1,8-naphthyridines and hydropyridopyrimidinone derivatives has been developed.",

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AU - Yang, Liupan

AU - Li, Jiarong

AU - Chai, Hongxin

AU - Lu, Hongyan

AU - Zhang, Qi

AU - Shi, Daxin

PY - 2013/4

Y1 - 2013/4

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AB - An efficient divergent synthesis of substituted 1,8-naphthyridine and hydropyridopyrimidinone derivatives was developed by the reactions of o-aminocyanopyridines and ketones based on different catalytic conditions. Catalyst-controlled cyclization pathways for the divergent synthesis of 1,8-naphthyridines and hydropyridopyrimidinone derivatives has been developed.

KW - 1,8-naphthyridine

KW - Friedländer annulations

KW - divergent synthesis

KW - hydropyridopyrimidinone

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M3 - Article

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JO - Chinese Journal of Chemistry

JF - Chinese Journal of Chemistry

IS - 4

ER -

A divergent synthesis of 1,8-naphthyridines and hydropyridopyrimidinones by the reactions of o-aminonitriles with ketones

Abstract

Keywords

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