罗汉果甜苷V的合成生物学研究进展

Translated title of the contribution: Synthetic biology for the synthesis of mogroside V - a review

Zemin Sun, Bo Lü*, Yongjun Feng*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

8 Citations (Scopus)

Abstract

Mogroside V, a component with high content and sweetness in mogrosides, has many pharmacological activities such as relieving cough, reducing sputum, anti-cancer, anti-oxidation, regulating blood sugar, making it a natural nonsugar sweetener with therapeutic functions, and showing a broad market prospect. However, the limited resources and high extraction costs have restricted its widespread use. The rapid development of synthetic biology has provided a new idea for the production of plant natural products. The low-cost and large-scale production will be realized through the construction of a microbial cell factory for mogroside V. Here, we briefly introduce the structure and pharmacological activity of mogroside V, and review progress in applying synthetic biology for its synthesis, and also discuss the challenges faced by the current research, to provide a reference for further studies on the biosynthesis of mogroside V.

Translated title of the contributionSynthetic biology for the synthesis of mogroside V - a review
Original languageChinese (Traditional)
Pages (from-to)2017-2028
Number of pages12
JournalShengwu Gongcheng Xuebao/Chinese Journal of Biotechnology
Volume36
Issue number10
DOIs
Publication statusPublished - 25 Oct 2020

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