栀子治疗脑缺血的研究进展

Translated title of the contribution: Research Progress of Gardeniae Fructus in Treatment of Cerebral Ischemia

Yun Wang, Dong Ying Li, Fan Kai Lin, De Peng Liu, Xue Zhang, Guo You Wang, Yin Lian Ma, Cun Zhang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Ischemic stroke is one of the diseases that seriously threaten human health. It is characterized by the high morbidity, disability rate and mortality, and has been lacking effective treatment. Its occurrence is related to metabolic disorder, calcium overload, free radical injury, inflammatory reaction, etc. Gardeniae Fructus not only has antipyretic, analgesic, hepatoprotective and cholagogic effects, but also has protective effects against ischemic brain injury. At present, there are more studies about the main components of Gardeniae Fructus against ischemic brain injury, but the mechanism is unclear. In this paper, the mechanism of the main active ingredients from Gardeniae Fructus in the treatment of cerebral ischemia injury in recent years was reviewed, and the effective component monomer and the whole were analyzed, so as to provide a basis for the prevention and treatment of ischemic brain injury of Gardeniae Fructus decoction pieces, and provide a reference for further research and application of this decoction pieces.

Translated title of the contributionResearch Progress of Gardeniae Fructus in Treatment of Cerebral Ischemia
Original languageChinese (Traditional)
Pages (from-to)226-234
Number of pages9
JournalChinese Journal of Experimental Traditional Medical Formulae
Volume25
Issue number24
DOIs
Publication statusPublished - 2019

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Wang, Y., Li, D. Y., Lin, F. K., Liu, D. P., Zhang, X., Wang, G. Y., Ma, Y. L., & Zhang, C. (2019). 栀子治疗脑缺血的研究进展. Chinese Journal of Experimental Traditional Medical Formulae, 25(24), 226-234. https://doi.org/10.13422/j.cnki.syfjx.20200349