基于多模态影像下的抑郁症大脑异常

In recent years, structural magnetic resonance imaging (sMRI) and functional magnetic resonance imaging (fMRI) are widely used in depression research. From the perspectives of morphology, structural network and functional network, the brain abnormalities of depression were explored to understand the pathogenesis, and to assist doctors in clinical diagnosis, treatment and prognosis. A large number of researches have found that the hippocampus and amygdala of depression showed different degrees of atrophy, and the connection strength of brain network and graph theory attributes showed significant abnormal. Moreover, the abnormal brain areas were related to emotional regulation, attention and cognitive control, and the degree of abnormalities were highly correlated with the severity of depression. The research actuality of depression from different perspectives was reviewed, and some suggestions for future research were put forward.