Wang Bai is an assistant professor (Special Associate researcher) at the School of Chemistry and Chemical Engineering, Beijing Institute of Technology. For many years, he has been engaged in the research of designing and synthesizing novel multifunctional fluorescent nanomaterials based on metal-organic framework for tumor diagnosis and treatment. Related results were published as first author (including tie for first place) in Angew.chem.in.ed., ACS Nano, Adv.Funct. Mater. Such as international famous journals, hosted the National Natural Science Foundation youth project 1.

He is mainly engaged in designing new multifunctional fluorescent nanomaterials based on metal-organic framework, and exploring their biomedical applications. His research mainly involves the interdisciplinary fields of nanomedicine, chemistry and pharmacy. Specific research contents include but are not limited to: 1. Development of targeted self-driven metal-organic frame nanomaterials for high-enrichment and deep-penetration anti-tumor therapy; 2. Development of efficient biomacromolecular nanocarriers based on metal-organic frameworks for immunotherapy; 3. Development of multifunctional fluorescent nanomaterials based on metal-organic framework for bone repair

2017.01-2021.05 Doctor of Engineering, Department of Chemical and Biomolecular Engineering, National University of Singapore
2012.09-2016.07 Tianjin University, Chemical Engineering and Technology major, Bachelor of Engineering

2021.06-present Assistant Professor, School of Chemistry and Chemical Engineering, Beijing Institute of Technology

Corresponding strategies were proposed to solve a series of problems, such as difficult accumulation of anticancer drugs in tumor sites, non-specific killing of anticancer drugs, reduced efficacy of anticancer drugs in tumor microenvironment, and non-specific activation of photosensitizers given throughout the body, so as to realize advanced anti-tumor therapy with high efficacy and low toxic side effects. Related results were published as first author (including tie for first place) in Angew.chem.in.ed., ACS Nano, Adv.Funct. Mater. And other internationally renowned journals.
1. Wang, Y.; Xu, S.; Shi, L.; Teh, C.; Qi, G.; Liu, B*. Cancer-Cell-Activated In-Situ Synthesis of Mitochondria-Targeting AIE Photosensitizer for Precise Photodynamic Therapy. Angew. Chem. Int. Ed. 2021, 60, 2-11.
2. Wang, Y.; Shi, L.; Ma, D.; Xu, S.; Wu, W.; Xu, L.; Panahandeh-Fard, M.; Zhu, X.; Wang, B.*; Liu, B*. Tumor-Activated and Metal-Organic Framework Assisted Self-Assembly of Organic Photosensitizers. ACS Nano 2020, 14, 13056–13068.
3. Wang, Y.; Wu, W.; Liu, J.; Manghnani, P. N.; Hu, F.; Ma, D.; Teh, C.; Wang, B.; Liu, B*. Cancer-Cell-Activated Photodynamic Therapy Assisted by Cu(II)-Based Metal-Organic Framework. ACS Nano 2019, 13, 6879-6890.
4. Wang, Y.; Shi, L.; Wu, W.; Qi, G.; Zhu, X.; Liu, B*. Tumor-Activated Photosensitization and Size Transformation of Nanodrugs. Adv. Funct. Mater. 2021, 31, 2010241.
5. Wang, Y.; Wu, W.; Mao, D.; Teh, C.; Wang, B.; Liu, B*. Metal-Organic Framework Assisted and Tumor Microenvironment Modulated Synergistic Image-Guided Photo-Chemo Therapy. Adv. Funct. Mater. 2020, 30, 2002431.
6. Wang, Y.; Liu, X.; Wu, W.; Mao, D.; Wang, B.; Tang, G.; Liu, B*. Mesoporous Rod-Like Metal-Organic Framework with Optimal Tumor Targeting Properties for Enhanced Activatable Photodynamic Therapy. Adv. Ther. 2020, 3, 2000011.
7. Zhang, X.; Wang, Y.; Liu, J.; Shi, J.; Mao, D.; Midgley, A. C.; Leng, X.; Kong, D.; Wang, Z*.; Liu, B*. Wang, S*. A Metal-Organic-Framework Incorporated Vascular Graft for Sustained Nitric Oxide Generation and Long-Term Vascular Patency. Chem. Eng. J. 2021, 421, 129577.