Jie Cao

He received his bachelor's and master's degrees from Nankai University in 1986 and 1989, and his doctorate degree from the University of Ottawa in 2001. From November 2000 to April 2002, he conducted postdoctoral research at the University of Ottawa, Canada, and returned to China in April 2002. From 2004 to 2009, Graduate School of Chinese Academy of Sciences engaged in the research of chiral drug chromatographic resolution methodology and chiral molecule recognition mass spectrometry; Since 2009, Beijing Institute of Technology has been mainly engaged in structural characterization of inorganic/organic/biomolecules, exploration of reaction mechanisms, and acceleration of organic/inorganic reactions on a microscopic scale by using interfacial catalytic effects.
Research projects undertaken and participated in as the main academic backbone: National Natural Science Foundation of China (21371025); Study Fund of Ministry of Education (Mass spectrometry study of Selegiline hydrochloride chiral drug with cyclodextrin); Key project of Ministry of Education (Mass spectrometry research on chiral drug molecular Recognition); 973 Pre-project research project (Research on the causes of persistent organic Pollutants pollution in the atmosphere); President's Foundation of Chinese Academy of Sciences (Mass Spectrometry for Molecular Recognition of chiral primary amines); Jilin Province Science and Technology Development Plan project (Discussion on pollution causes and countermeasures of chlorobenzene persistent organic Pollutants in the atmosphere).
He has taught "Analytical Chemistry", "Modern Material Analysis Technology", "Life Analytical Chemistry", "Analytical Chemistry Experiment", "Modern Instrumental Analysis", "Modern Chemistry Special Lecture", "Organic Structure Analysis", "Organic Matter Spectrum Principle and Application", "Chromatographic and Spectral Experiment Course", "Modern Chromatography-mass Spectrometry Analysis Method and Experiment" and "Organic Spectrum Analysis" and other undergraduate students Graduate studies. He has won the Excellent Course Award of the Graduate School of the Chinese Academy of Sciences, the first batch of Outstanding Contributions to centralized teaching of the Graduate School and the second prize of the Teaching Achievement Award of the Chinese Academy of Sciences in 2008. He has published 38 SCI papers as the first author and obtained 2 national invention patents.

(1) Mass Spectrum
 Structural characterization of inorganic/organic/biomolecules
 Reaction Mechanism Study
 Chiral recognition
 interfacial Catalysis and Reaction mass spectrometry
(2) Chromatography
 Separation of Chiral Compounds by chromatography
(3) Controlled synthesis of nanocatalysts and their applications in environmental pollutant removal

See Personal profile

See Personal profile

PUBLICATIONS 1.Y. Yu, M.X. Wang, M.Z. Li, L.M. Zhang, J.G. Zhao, J. Cao*, and W.Z. Wang*. Controlled Recognition and Corona Formation by Cascade Micellar Nanoprobes: for Boosting Glioma Theranostics, Anal. Chem. 2022, 94, 11118-11123.
2. Heyuan Jia, Bo Yao, Shi Chen 稆, Shi Fang Lu, Jie Cao *, Free radical mediated selective CC bond breaking and isomer differentiation in peptide derivatives, Chinese Journal of Mass Spectrometry, 2022, 43, 44-55.
3. Lu Shi-Fang, Chen Shi-稆, Cao Jie *, Sun Shuo-Qi, Formation and dissociation mechanism of aromatic amino acid tripeptides and their derivatives, Chinese Journal of Mass Spectrometry, 2020, 41, 569-576.
4. Lu Shi-Fang, CAO Jie *, Jia He-Yuan, Sun Shuo-Qi, Chen Shi-Chen 稆*, Mechanism of formation, isomeric and dissociative reactions of tyrosine-containing tripeptide radicals, Science in China: Chemistry, 2020, 50,1177-1186.
5.J. Cao*, Q.Q. Wang, S.Q. An, S.F. Lu and Q.Z. Jia, Facile and efficient preparation of organoimido derivatives of [Mo6O19]2- using accelerated reactions in Leidenfrost droplets, Analyst, 2020, 145, 4844-4851.
6.S.Q. An, S. Liu, J. Cao*, S.F. Lu, Nitrogen-Activated Oxidation in Nitrogen Direct Analysis in Real Time Mass Spectrometry (DART-MS) and Rapid Detection of Explosives Using Thermal Desorption DART-MS, J. Am. Soc. Mass Spectrom., 2019, 30, 2092-2100.
7.Y.X. Fan, S.F. Lu, J. Cao*, A novel inorganic-organic hybrid complex between polyoxometalate and cyclodextrin: Synthesis, structure and catalytic activity, Int. J. Mass Spectrom., 2019, 435, 163-167.
8.J. Cao*, Q.Q. Wang, C. Liu, S.Q., An, Gas-phase chemistry of arylimido-functionalized hexamolybdates [Mo6O19]2−. J. Am. Soc. Mass Spectrom., 2018, 29, 1331-1334.
9.J. Cao*, C. Liu, Q.Q. Wang, Y.Z. Li, Q. Yu, A novel catalytic application of heteropolyacids: chemical transformation of major ginsenosides into rare ginsenosides exemplified by Rg1. Sci. China Chem., 2017, 60 (6): 748–753.
10.C. Liu, J. Cao*, Q.Q. Wang, and J.C. Zang, C.G. Ci*. Effect of vanadium valence state on the solution chemistry and the stability of vanadium substituted polyoxometalates. RSC Adv., 2016, 6, 110922-110927.
11.J. Cao*, C. Liu and Q.D. Jia. Complex solution chemistry behind the simple “one-pot” synthesis of vanadium-substituted polyoxometalates unraveled by electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom., 2016, 30 (Suppl. 1), 14-19.
12.L.Y. Fan, Y.Y. Hong, J. Cao* and C.W. Hu*. Investigation into the mechanism of polyoxotungstates-catalyzed cyclooctene epoxidation by ESI-MS. RSC Adv., 2016, 6, 56656-56660.
13.J. Cao*, C. Xu, C. Liu, W.Q. Liu. Cation-anion interactions and synergistic catalysis by supramolecular polyoxometalate complexes [C10H18N]n[XM12O40]. ChemistrySelect, 2016, 6, 1268-1272.
14.L.Y. Fan†, Z.G. Lin†, J. Cao* and C.W. Hu*. Probing the self-assembly mechanism of Lanthanide-containing sandwich-Type silicotungstates [{Ln(H2O)n}2{Mn4(B-α-SiW9O34)2(H2O)2}]6 -- using time-resolved mass spectrometry and X-ray crystallography. Inorg. Chem., 2016, 55 (6), 2900-2908 (†Equal contribution).