Abstract
A pyridylvinylene derivative containing piazselenole displayed high selectivity toward glutathione in the presence of other biorelevant analytes. The compound exhibited a 19 nm red-shift in absorption spectra and ∼3-fold fluorescence intensity enhancement; in addition, it was possible to detect micromolar amounts of glutathione quantitatively using both red-shift absorbance and enhanced fluorescence. The mechanism of the reaction between the modified pyridylvinylene derivative and glutathione was confirmed using ESI-MS and absorption/fluorescence spectra.
Original language | English |
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Pages (from-to) | 87-92 |
Number of pages | 6 |
Journal | Dyes and Pigments |
Volume | 86 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jun 2010 |
Keywords
- Fluorescence enhancement
- Glutathione
- Intramolecular charge transfer
- Red-shift
- Thiol probe
- Two-channel