Abstract
Hydrophilic uridine molecularly imprinted core-shell structured polymers (MIPs) were prepared via the distillation precipitation polymerization method using uridine, methyl methacrylate, ethylene glycol dimethacrylate, and 2, 2-azobisisobutyronitrile as the template molecule, functional monomer, cross-linker, and initiator, respectively. The adsorption kinetic behavior, equilibrium, and selectivity of uridine onto the MIPs were investigated by conducting a series of batch adsorption experiments. The results showed that the pseudo-first-order kinetic model provided a good correlation for the adsorption of uridine onto MIPs. The linear correlation coefficient R 2 was 0.9884. The Langmuir and Freundlich modeling of the adsorption showed that the adsorption of the imprinted molecule uridine onto MIPs was fitted well to the Freundlich equation. The R 2 value was 0.980. The separation capability of the MIPs to uridine and its analog was evaluated as HPLC column filling. The MIPs chromatographic column has a selectively distinguishing ability for uridine and its analog.
| Original language | English |
|---|---|
| Pages (from-to) | 38-47 |
| Number of pages | 10 |
| Journal | International Journal of Polymer Analysis and Characterization |
| Volume | 17 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 2012 |
Keywords
- Adsorption kinetics
- Hydrophilic molecularly imprinted core-shell structured polymers
- Isotherms
- Selective adsorption
- Uridine