Switchable boronate affinity materials for thermally modulated capture, separation and enrichment of cis-diol biomolecules

Zongjian Liu; Kaleem Ullah; Liping Su; Fang Lv; Yulin Deng; Rongji Dai; Yujuan Li; Yukui Zhang

doi:10.1039/c2jm33578f

Switchable boronate affinity materials for thermally modulated capture, separation and enrichment of cis-diol biomolecules

Zongjian Liu, Kaleem Ullah, Liping Su, Fang Lv, Yulin Deng^*, Rongji Dai, Yujuan Li, Yukui Zhang

^*Corresponding author for this work

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Abstract

A new thermoresponsive boronate affinity chromatographic material, P(N-isopropylacrylamide-4-vinylphenylboronic acid) P(NIPAAm-co-VPBA) grafted silica featuring a thermally switchable property, was prepared and successfully employed for the specific capture-release of cis-diol biomolecules with simpler adjustment to the temperature instead of the conventional need to change the pH of the mobile phase.

Original language	English
Pages (from-to)	18753-18756
Number of pages	4
Journal	Journal of Materials Chemistry
Volume	22
Issue number	36
DOIs	https://doi.org/10.1039/c2jm33578f
Publication status	Published - 28 Sept 2012

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abstract = "A new thermoresponsive boronate affinity chromatographic material, P(N-isopropylacrylamide-4-vinylphenylboronic acid) P(NIPAAm-co-VPBA) grafted silica featuring a thermally switchable property, was prepared and successfully employed for the specific capture-release of cis-diol biomolecules with simpler adjustment to the temperature instead of the conventional need to change the pH of the mobile phase.",

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AU - Liu, Zongjian

AU - Ullah, Kaleem

AU - Su, Liping

AU - Lv, Fang

AU - Deng, Yulin

AU - Dai, Rongji

AU - Li, Yujuan

AU - Zhang, Yukui

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AB - A new thermoresponsive boronate affinity chromatographic material, P(N-isopropylacrylamide-4-vinylphenylboronic acid) P(NIPAAm-co-VPBA) grafted silica featuring a thermally switchable property, was prepared and successfully employed for the specific capture-release of cis-diol biomolecules with simpler adjustment to the temperature instead of the conventional need to change the pH of the mobile phase.

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Switchable boronate affinity materials for thermally modulated capture, separation and enrichment of cis-diol biomolecules

Abstract

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