Stabilization of Grignard reagents by a pillar[5]arene host-Schlenk equilibria and Grignard reactions

Lingyi Shen, Yanxia Zhao, Dihua Dai, Ying Wei Yang*, Biao Wu, Xiao Juan Yang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

Grignard reagents (RMgX) are widely used in organic synthesis. However, these highly reactive compounds are supplied in inflammable solvents, which causes extra complexity in their transportation. Herein we report that Grignard reagents with linear alkyl chains can be entrapped and stabilized by the macrocyclic host pillar[5]arene while preserving their reactivity.

Original languageEnglish
Pages (from-to)1381-1384
Number of pages4
JournalChemical Communications
Volume56
Issue number9
DOIs
Publication statusPublished - 2020
Externally publishedYes

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