Spatial-spectral density peaks based discriminant projection for classification of membranous nephropathy hyperspectral pathological image

Meng Lv, Wei Li*, Ran Tao

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Microscopic hyperspectral imaging has become an emerging technique for various medical applications. However, high dimensionality of hyperspectral image (HSI) makes image processing and extraction of important diagnostic information challenging. In this paper, a novel dimensionality reduction method named spatial-spectral density peaks based discriminant projection (SSDP) is proposed by considering spatial-spectral density distribution characteristics of immune complexes. The proposed SSDP coupled with support vector machine classifier (SVM) yields high-precision automatic diagnosis of membranous nephropathy (MN). Detailed ex-vivo validation of the proposed method demonstrates the potential clinical value of the system in identifying hepatitis B virus-associated membranous nephropathy (HBV-MN) and primary membranous nephropathy (PMN).

Original languageEnglish
Title of host publicationFrontiers in Artificial Intelligence and Applications
EditorsAntonio J. Tallon-Ballesteros
PublisherIOS Press BV
Pages160-167
Number of pages8
ISBN (Electronic)9781643681344
DOIs
Publication statusPublished - 2020
Event6th International Conference on Fuzzy Systems and Data Mining, FSDM 2020 - Virtual, Online, China
Duration: 13 Nov 202016 Nov 2020

Publication series

NameFrontiers in Artificial Intelligence and Applications
Volume331
ISSN (Print)0922-6389
ISSN (Electronic)1879-8314

Conference

Conference6th International Conference on Fuzzy Systems and Data Mining, FSDM 2020
Country/TerritoryChina
CityVirtual, Online
Period13/11/2016/11/20

Keywords

  • Dimensionality reduction
  • feature extraction
  • membranous nephropathy diagnosis
  • microscopic hyperspectral imaging

Fingerprint

Dive into the research topics of 'Spatial-spectral density peaks based discriminant projection for classification of membranous nephropathy hyperspectral pathological image'. Together they form a unique fingerprint.

Cite this