SDoF-Net: Super Depth of Field Network for Cell Detection in Leucorrhea Micrograph

Xiaohui Du, Xiangzhou Wang, Guangming Ni*, Jing Zhang, Ruqian Hao, Jiaxi Zhao, Xudong Wang, Juanxiu Liu, Lin Liu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Accompanied with the rapid increase of the demand for routine examination of leucorrhea, efficiency and accuracy become the primary task. However, in super depth of field (SDoF) system, the problem of automatic detection and localization of cells in leucorrhea micro-images is still a big challenge. The changing of the relative position between the cell center and focus plane of microscope lead to variable cell morphological structure in the two-dimensional image, which is an important reason for the low accuracy of current deep learning target detection algorithms. In this paper, an object detection method based on Retinanet in state of super depth of field is proposed, which can achieve high precision detecting of leucorrhea components by the SDoF feature aggregation module. Compared with the current mainstream algorithms, the mean average accuracy (mAP) index has been improved significantly, the mAP index is 82.7% for SDoF module and 83.0% for SDoF+ module, with an average increase of more than 10%. These improved features can significantly improve the efficiency and accuracy of the algorithm. The algorithm proposed in this paper can be integrated into the leucorrhea automatic detection system.

Original languageEnglish
Pages (from-to)1229-1238
Number of pages10
JournalIEEE Journal of Biomedical and Health Informatics
Volume26
Issue number3
DOIs
Publication statusPublished - 1 Mar 2022
Externally publishedYes

Keywords

  • Bio-micrograph
  • Object detection
  • Retinanet
  • Super-depth-of-field

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