Numerical modeling of injection flow of drug agents for controlled drug delivery

Moubin Liu; Jianzhong Chang; Huiqi Li

doi:10.1109/IEMBS.2007.4352500

Numerical modeling of injection flow of drug agents for controlled drug delivery

Moubin Liu^*, Jianzhong Chang, Huiqi Li

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

3 Citations (Scopus)

Abstract

Multiphase flow dynamics for drug delivery is significant in controlling the release of therapeutic agents at pre-determined rates to specific target sites. This paper presents the numerical investigation of injection flow of drug agents for controlled drug delivery using an improved dissipative particle dynamics (DPD) method. This DPD method employs a new conservative particle-particle interaction combining short-range repulsion and long-range attraction to simulate micro- or meso-scale multiphase flow dynamics. It is shown that the improved DPD method is capable of modeling injection flows of drug agents with different flow modes.

Original language	English
Title of host publication	29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Pages	1152-1155
Number of pages	4
DOIs	https://doi.org/10.1109/IEMBS.2007.4352500
Publication status	Published - 2007
Externally published	Yes
Event	29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France Duration: 23 Aug 2007 → 26 Aug 2007

Publication series

Name	Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ISSN (Print)	0589-1019

Conference

Conference	29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Country/Territory	France
City	Lyon
Period	23/08/07 → 26/08/07

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10.1109/IEMBS.2007.4352500

Cite this

Liu, M., Chang, J., & Li, H. (2007). Numerical modeling of injection flow of drug agents for controlled drug delivery. In 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 (pp. 1152-1155). Article 4352500 (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings). https://doi.org/10.1109/IEMBS.2007.4352500

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title = "Numerical modeling of injection flow of drug agents for controlled drug delivery",

abstract = "Multiphase flow dynamics for drug delivery is significant in controlling the release of therapeutic agents at pre-determined rates to specific target sites. This paper presents the numerical investigation of injection flow of drug agents for controlled drug delivery using an improved dissipative particle dynamics (DPD) method. This DPD method employs a new conservative particle-particle interaction combining short-range repulsion and long-range attraction to simulate micro- or meso-scale multiphase flow dynamics. It is shown that the improved DPD method is capable of modeling injection flows of drug agents with different flow modes.",

author = "Moubin Liu and Jianzhong Chang and Huiqi Li",

year = "2007",

doi = "10.1109/IEMBS.2007.4352500",

language = "English",

isbn = "1424407885",

series = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",

pages = "1152--1155",

booktitle = "29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07",

note = "29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 ; Conference date: 23-08-2007 Through 26-08-2007",

}

Liu, M, Chang, J & Li, H 2007, Numerical modeling of injection flow of drug agents for controlled drug delivery. in 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07., 4352500, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, pp. 1152-1155, 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07, Lyon, France, 23/08/07. https://doi.org/10.1109/IEMBS.2007.4352500

Numerical modeling of injection flow of drug agents for controlled drug delivery. / Liu, Moubin; Chang, Jianzhong; Li, Huiqi.
29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07. 2007. p. 1152-1155 4352500 (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Liu, Moubin

AU - Chang, Jianzhong

AU - Li, Huiqi

PY - 2007

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N2 - Multiphase flow dynamics for drug delivery is significant in controlling the release of therapeutic agents at pre-determined rates to specific target sites. This paper presents the numerical investigation of injection flow of drug agents for controlled drug delivery using an improved dissipative particle dynamics (DPD) method. This DPD method employs a new conservative particle-particle interaction combining short-range repulsion and long-range attraction to simulate micro- or meso-scale multiphase flow dynamics. It is shown that the improved DPD method is capable of modeling injection flows of drug agents with different flow modes.

AB - Multiphase flow dynamics for drug delivery is significant in controlling the release of therapeutic agents at pre-determined rates to specific target sites. This paper presents the numerical investigation of injection flow of drug agents for controlled drug delivery using an improved dissipative particle dynamics (DPD) method. This DPD method employs a new conservative particle-particle interaction combining short-range repulsion and long-range attraction to simulate micro- or meso-scale multiphase flow dynamics. It is shown that the improved DPD method is capable of modeling injection flows of drug agents with different flow modes.

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DO - 10.1109/IEMBS.2007.4352500

M3 - Conference contribution

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AN - SCOPUS:57649224068

SN - 1424407885

SN - 9781424407880

T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

SP - 1152

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BT - 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07

T2 - 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07

Y2 - 23 August 2007 through 26 August 2007

ER -

Numerical modeling of injection flow of drug agents for controlled drug delivery

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