Novel biodegradable copolyesters poly (butylene succinate-co-butylene aspartic acid) with functional amine pendent groups

Biomaterials with functional lateral groups have attracted considerable attention. A novel biodegradable aliphatic copolyester poly (butylene succinate-co-CBz-butylene aspartic acid) (P (BS-co-BCD)) has been synthesized through a condensation copolymerization based on N-Benzyloxycarbonyl (CBz)-L-aspartic acid, succinic acid and 1, 4-butanediol. The copolymer P (BS-co-BD) containing functional amino groups on the side chain, was achieved through consequently Pd/C catalyzed hydrogenation reaction. The resultant copolyester was characterized by gel permeation in chromatography (GPC), fourier transform infrared spectroscopic (FT-IR) and nuclear magnetic resonance (NMR) spectrum. The water contact angles of the copolymers were lower than those of poly (butylene succinate) polyester (PBS), which indicated that the hydrophilicity of copolymers have been greatly improved for the introducing of aspartic acid chains than that of PBS.