New conversion of Friendländer reaction of 3-amino-1H-benzo[f]chromene-2-carbonitriles with cyclohexanone

Jia Rong Li; Li Jun Zhang; Xi Quan Yang; Qing Li; Dong Wang; Chun Xia Wang; Da Xin Shi; Qi Zhang

doi:10.1016/j.cclet.2007.11.003

New conversion of Friendländer reaction of 3-amino-1H-benzo[f]chromene-2-carbonitriles with cyclohexanone

Jia Rong Li^*, Li Jun Zhang, Xi Quan Yang, Qing Li, Dong Wang, Chun Xia Wang, Da Xin Shi, Qi Zhang

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Two different skeletons of heterocyclic compounds, quinoline and quinazolinone analogs could be obtained by a novel one-pot synthesis from substituted 3-amino-1H-benzo[f]chromene-2-carbonitrile derivatives and cyclohexanone in DMF in the catalyst of anhydrous zinc chloride under reflux. A plausible mechanism was proposed.

Original language	English
Pages (from-to)	15-18
Number of pages	4
Journal	Chinese Chemical Letters
Volume	19
Issue number	1
DOIs	https://doi.org/10.1016/j.cclet.2007.11.003
Publication status	Published - Jan 2008

Keywords

Friedländer cyclocondensation
New conversion
Quinoline and quinazolinone analogs

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10.1016/j.cclet.2007.11.003

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title = "New conversion of Friendl{\"a}nder reaction of 3-amino-1H-benzo[f]chromene-2-carbonitriles with cyclohexanone",

abstract = "Two different skeletons of heterocyclic compounds, quinoline and quinazolinone analogs could be obtained by a novel one-pot synthesis from substituted 3-amino-1H-benzo[f]chromene-2-carbonitrile derivatives and cyclohexanone in DMF in the catalyst of anhydrous zinc chloride under reflux. A plausible mechanism was proposed.",

keywords = "Friedl{\"a}nder cyclocondensation, New conversion, Quinoline and quinazolinone analogs",

author = "Li, {Jia Rong} and Zhang, {Li Jun} and Yang, {Xi Quan} and Qing Li and Dong Wang and Wang, {Chun Xia} and Shi, {Da Xin} and Qi Zhang",

year = "2008",

month = jan,

doi = "10.1016/j.cclet.2007.11.003",

language = "English",

volume = "19",

pages = "15--18",

journal = "Chinese Chemical Letters",

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T1 - New conversion of Friendländer reaction of 3-amino-1H-benzo[f]chromene-2-carbonitriles with cyclohexanone

AU - Li, Jia Rong

AU - Zhang, Li Jun

AU - Yang, Xi Quan

AU - Li, Qing

AU - Wang, Dong

AU - Wang, Chun Xia

AU - Shi, Da Xin

AU - Zhang, Qi

PY - 2008/1

Y1 - 2008/1

N2 - Two different skeletons of heterocyclic compounds, quinoline and quinazolinone analogs could be obtained by a novel one-pot synthesis from substituted 3-amino-1H-benzo[f]chromene-2-carbonitrile derivatives and cyclohexanone in DMF in the catalyst of anhydrous zinc chloride under reflux. A plausible mechanism was proposed.

AB - Two different skeletons of heterocyclic compounds, quinoline and quinazolinone analogs could be obtained by a novel one-pot synthesis from substituted 3-amino-1H-benzo[f]chromene-2-carbonitrile derivatives and cyclohexanone in DMF in the catalyst of anhydrous zinc chloride under reflux. A plausible mechanism was proposed.

KW - Friedländer cyclocondensation

KW - New conversion

KW - Quinoline and quinazolinone analogs

UR - http://www.scopus.com/inward/record.url?scp=37549013349&partnerID=8YFLogxK

U2 - 10.1016/j.cclet.2007.11.003

DO - 10.1016/j.cclet.2007.11.003

M3 - Article

AN - SCOPUS:37549013349

SN - 1001-8417

VL - 19

SP - 15

EP - 18

JO - Chinese Chemical Letters

JF - Chinese Chemical Letters

IS - 1

ER -

New conversion of Friendländer reaction of 3-amino-1H-benzo[f]chromene-2-carbonitriles with cyclohexanone

Abstract

Keywords

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