Mn-doped CdS/ZnS/CdS QD-based fluorescent nanosensor for rapid, selective, and ultrasensitive detection of copper(ii) ion

Xiaoman Zhai, Yunqian Gong, Wen Yang, Huaizhi Kang*, Xiaoling Zhang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

A facile strategy for designing a glutathione-capped Mn-doped CdS/ZnS/CdS core/shell/shell QD-based fluorescent nanosensor has been developed for rapid, selective, and ultrasensitive detection of Cu2+. In this nanosensor, glutathione provided the binding and recognition sites for Cu2+, accumulating Cu2+ on the QD surface. The energy transfer pathway from the host to the Mn dopant was sensitive to the interferences from non-radiative recombination pathways caused by Cu2+, resulting in photoluminescence quenching. The nanosensor responded to Cu2+ within one minute and exhibited good selectivity to Cu2+ over other metal ions and good linear correlation over the concentration range of 1 nM to 100 nM, with a detection limit as low as 0.74 nM. Moreover, this nanosensor avoids the self-quenching problem and autofluorescence in biosystems due to the substantial Stokes shift and long lifetime, and thus can be used to monitor Cu2+ in living cells.

Original languageEnglish
Pages (from-to)63458-63464
Number of pages7
JournalRSC Advances
Volume5
Issue number78
DOIs
Publication statusPublished - 2015

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