Abstract
Chronic wound caused by diabetes is an important cause of disability and seriously affects the quality of life of patients. Therefore, it is of great clinical significance to develop a wound dressing that can accelerate the healing of diabetic wounds. Nanoparticles have great advantages in promoting diabetic wound healing due to their antibacterial properties, low cytotoxicity, good biocompatibility and drug delivery ability. Adding nanoparticles to the dressing matrix and using nanoparticles to deliver drugs and cytokines to promote wound healing has proven to be effective. This review will focus on the effects of diabetes on wound healing, introduce the properties, preparation methods and action mechanism of nanoparticles in wound healing, and describe the effects and application status of various nanoparticle-loaded dressings in diabetes-related chronic wound healing.
| Original language | English |
|---|---|
| Pages (from-to) | 2097-2119 |
| Number of pages | 23 |
| Journal | International Journal of Nanomedicine |
| Volume | 17 |
| DOIs | |
| Publication status | Published - 2022 |
Keywords
- antibacterial
- diabetic wound healing
- drug delivery
- good biocompatibility
- low cytotoxicity
- nanoparticles
