@inproceedings{5882bfd216964ef892f9bc2f702a4784,
title = "Effect of de-noising and DDRV correction on cone-beam SPECT reconstruction with non-uniform attenuation",
abstract = "SPECT (single photon emission computed tomography) is a non-invasive, cost-effective means for assessment of tissue/organ functions in nuclear medicine. For more accurate diagnosis, quantitative reconstruction of radiotracer concentration at any location inside the body is desired. To achieve this goal, we have to address a number of factors that significantly degrade the acquired projection data. The cone-beam SPECT system has higher resolution comparing with parallel-beam and fan-beam SPECT, which is highly advantageous in small object detection. In this paper, we used four analytical reconstruction schemes for cone-beam SPECT that allow simultaneous compensation for non-uniform attenuation and distance-dependent resolution variation (DDRV), as well as accurate treatment of Poisson noise. The simulation results show that the reconstruction scheme 1 and 4 both can obtain good reconstruction results.",
keywords = "Poisson noise, DDRV, SPECT, cone-beam, non-uniform attenuation, reconstruction",
author = "Hao Zhang and Junhai Wen and Wen Yin and Cuifen Li and Kangping Zhang and Zhengrong Liang",
year = "2011",
doi = "10.1117/12.877352",
language = "English",
isbn = "9780819485038",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Medical Imaging 2011",
note = "Medical Imaging 2011: Physics of Medical Imaging ; Conference date: 13-02-2011 Through 17-02-2011",
}