Abstract
The effect of borane source on enantioselectivity in the enantiopure oxazaborolidine-catalyzed asymmetric borane reduction of ketones has been investigated by using (S)-3,1,2-oxazaborobicyclo[3.3.0]octane and (S)-7,3,1,2-thiaxazaborobicyclo[3.3.0]octane as catalysts. The results indicate that the enantioselective order of different borane sources is borane-dimethyl sulfide < borane-N,N-diethylaniline < borane-THF for the asymmetric reduction of a ketone under the same conditions.
| Original language | English |
|---|---|
| Pages (from-to) | 740-746 |
| Number of pages | 7 |
| Journal | Heteroatom Chemistry |
| Volume | 18 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 2007 |
| Externally published | Yes |
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Wang, X., Du, J., Liu, H., Du, D. M., & Xu, J. (2007). Effect of borane source on the enantioselectivity in the enantiopure oxazaborolidine-catalyzed asymmetric borane reduction of ketones. Heteroatom Chemistry, 18(7), 740-746. https://doi.org/10.1002/hc.20370