Cystoscopic optical coherence tomography for urinary bladder imaging in vivo

Z. G. Wang*, H. Adler, D. Chan, A. Jain, H. K. Xie, Z. L. Wu, Y. T. Pan

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Citations (Scopus)

Abstract

This paper summarizes the development of new 2D MEMS mirrors and the pertinent modification to improve OCT endoscopic catheter packaging suitable for in vivo imaging diagnosis of bladder cancers. Comparative study of the newly developed endocopic OCT versus the bench-top OCT is presented. Results of in vivo OCT cystoscopy based on a porcine acute inflammation model are presented to compare time-domain OCT and spectral-domain OCT for in vivo imaging. In addition, results of spectral-domain Doppler OCT are presented to image blood flow in the lamina propria of the bladder. The results of our in vivo animal study using the presented OCT endoscope are discussed for potential problems in the future clinical applications.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
DOIs
Publication statusPublished - 2006
Externally publishedYes
EventCoherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X - San Jose, CA, United States
Duration: 23 Jan 200625 Jan 2006

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume6079
ISSN (Print)0277-786X

Conference

ConferenceCoherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X
Country/TerritoryUnited States
CitySan Jose, CA
Period23/01/0625/01/06

Keywords

  • Backscattering
  • Bladder tumor
  • Laser scanning cystoscopy
  • MEMS mirror
  • Optical coherence Doppler tomography
  • Optical coherence tomography
  • Optical modeling

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