Calcium channel blockers and Alzheimer's disease

Yi Tan; Yulin Deng; Hong Qing

doi:10.3969/j.issn.1673-5374.2012.02.010

Calcium channel blockers and Alzheimer's disease

Yi Tan, Yulin Deng, Hong Qing^*

^*Corresponding author for this work

School of Medical and Technology

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Alzheimer's disease is characterized by two pathological hallmarks: amyloid plaques and neurofibrillary tangles. In addition, calcium homeostasis is disrupted in the course of human aging. Recent research shows that dense plaques can cause functional alteration of calcium signals in mice with Alzheimer's disease. Calcium channel blockers are effective therapeutics for treating Alzheimer's disease. This review provides an overview of the current research of calcium channel blockers involved in Alzheimer's disease therapy.

Original language	English
Pages (from-to)	137-140
Number of pages	4
Journal	Neural Regeneration Research
Volume	7
Issue number	2
DOIs	https://doi.org/10.3969/j.issn.1673-5374.2012.02.010
Publication status	Published - Jan 2012

Keywords

Alzheimer's disease
Alzheimer's disease pathogenesis
Calcium channel
Calcium channel blocker
Calcium homeostasis
β-amyloid

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3969/j.issn.1673-5374.2012.02.010

Cite this

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abstract = "Alzheimer's disease is characterized by two pathological hallmarks: amyloid plaques and neurofibrillary tangles. In addition, calcium homeostasis is disrupted in the course of human aging. Recent research shows that dense plaques can cause functional alteration of calcium signals in mice with Alzheimer's disease. Calcium channel blockers are effective therapeutics for treating Alzheimer's disease. This review provides an overview of the current research of calcium channel blockers involved in Alzheimer's disease therapy.",

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KW - Alzheimer's disease pathogenesis

KW - Calcium channel

KW - Calcium channel blocker

KW - Calcium homeostasis

KW - β-amyloid

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Calcium channel blockers and Alzheimer's disease

Abstract

Keywords

UN SDGs

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