A portable illumination device for photodynamic therapy of the oral cavity

Jiyuan Xiong; Xu Wang; Xiaoming Hu; Ying Han; Qin Li

doi:10.1142/S1793545822400120

A portable illumination device for photodynamic therapy of the oral cavity

Jiyuan Xiong, Xu Wang, Xiaoming Hu^*, Ying Han^*, Qin Li

^*Corresponding author for this work

School of Medical and Technology

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Photodynamic therapy (PDT) is a minimally invasive method for treating oral leukoplakia. In this paper, we propose a portable PDT device consisting of a flexible circuit board with a liquid flow cooling module on the back. The light source size was 17mm×11mm×4mm×11mm×4mm, and the irradiation area of the light source was up to 100mm2. The irradiance range of this device was from 10mW/cm2 to 100mW/cm2. Simulation and experimental results showed that the irradiance coefficient variation for a treatment area of 81mm2 was less than 7%. At an irradiance of 100mW/cm2, a device surface temperature of lower than 42∘C can be achieved to satisfy the safety requirements under the conditions that the temperature of cooling liquid is 10∘C and the liquid flow speed is above 12mL/min.

Original language	English
Article number	2240012
Journal	Journal of Innovative Optical Health Sciences
Volume	15
Issue number	6
DOIs	https://doi.org/10.1142/S1793545822400120
Publication status	Published - 1 Nov 2022

Keywords

Photodynamic therapy
illumination device
irradiance uniformity
oral leukoplakia

Access to Document

10.1142/S1793545822400120

Cite this

@article{c144758bb76a45099f6841b191c9b35c,

title = "A portable illumination device for photodynamic therapy of the oral cavity",

abstract = "Photodynamic therapy (PDT) is a minimally invasive method for treating oral leukoplakia. In this paper, we propose a portable PDT device consisting of a flexible circuit board with a liquid flow cooling module on the back. The light source size was 17mm×11mm×4mm×11mm×4mm, and the irradiation area of the light source was up to 100mm2. The irradiance range of this device was from 10mW/cm2 to 100mW/cm2. Simulation and experimental results showed that the irradiance coefficient variation for a treatment area of 81mm2 was less than 7%. At an irradiance of 100mW/cm2, a device surface temperature of lower than 42∘C can be achieved to satisfy the safety requirements under the conditions that the temperature of cooling liquid is 10∘C and the liquid flow speed is above 12mL/min.",

keywords = "Photodynamic therapy, illumination device, irradiance uniformity, oral leukoplakia",

author = "Jiyuan Xiong and Xu Wang and Xiaoming Hu and Ying Han and Qin Li",

note = "Publisher Copyright: {\textcopyright} 2022 The Author(s).",

year = "2022",

month = nov,

day = "1",

doi = "10.1142/S1793545822400120",

language = "English",

volume = "15",

journal = "Journal of Innovative Optical Health Sciences",

issn = "1793-5458",

publisher = "World Scientific",

number = "6",

}

TY - JOUR

T1 - A portable illumination device for photodynamic therapy of the oral cavity

AU - Xiong, Jiyuan

AU - Wang, Xu

AU - Hu, Xiaoming

AU - Han, Ying

AU - Li, Qin

PY - 2022/11/1

Y1 - 2022/11/1

N2 - Photodynamic therapy (PDT) is a minimally invasive method for treating oral leukoplakia. In this paper, we propose a portable PDT device consisting of a flexible circuit board with a liquid flow cooling module on the back. The light source size was 17mm×11mm×4mm×11mm×4mm, and the irradiation area of the light source was up to 100mm2. The irradiance range of this device was from 10mW/cm2 to 100mW/cm2. Simulation and experimental results showed that the irradiance coefficient variation for a treatment area of 81mm2 was less than 7%. At an irradiance of 100mW/cm2, a device surface temperature of lower than 42∘C can be achieved to satisfy the safety requirements under the conditions that the temperature of cooling liquid is 10∘C and the liquid flow speed is above 12mL/min.

AB - Photodynamic therapy (PDT) is a minimally invasive method for treating oral leukoplakia. In this paper, we propose a portable PDT device consisting of a flexible circuit board with a liquid flow cooling module on the back. The light source size was 17mm×11mm×4mm×11mm×4mm, and the irradiation area of the light source was up to 100mm2. The irradiance range of this device was from 10mW/cm2 to 100mW/cm2. Simulation and experimental results showed that the irradiance coefficient variation for a treatment area of 81mm2 was less than 7%. At an irradiance of 100mW/cm2, a device surface temperature of lower than 42∘C can be achieved to satisfy the safety requirements under the conditions that the temperature of cooling liquid is 10∘C and the liquid flow speed is above 12mL/min.

KW - Photodynamic therapy

KW - illumination device

KW - irradiance uniformity

KW - oral leukoplakia

UR - http://www.scopus.com/inward/record.url?scp=85141940619&partnerID=8YFLogxK

U2 - 10.1142/S1793545822400120

DO - 10.1142/S1793545822400120

M3 - Article

AN - SCOPUS:85141940619

SN - 1793-5458

VL - 15

JO - Journal of Innovative Optical Health Sciences

JF - Journal of Innovative Optical Health Sciences

IS - 6

M1 - 2240012

ER -

A portable illumination device for photodynamic therapy of the oral cavity

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this