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X2-Gait: A Framework for Dual-Level Interpretable Gait-Based Subthreshold Depression Recognition

  • Haoran Gao
  • , Shuo Zhang
  • , Chenyang Lu
  • , Zengyu Zhang
  • , Qi Li
  • , Yanan Zhang*
  • , Jian Shen*
  • , Bin Hu*
  • *此作品的通讯作者
  • Ministry of Education in China
  • Beijing Institute of Technology

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

Early subthreshold depression identification is critical for intervention but hampered by subjective assessments. Gait analysis offers a promising objective biomarker, but existing computational methods struggle to integrate multi-scale motor patterns and lack the interpretability required for clinical trust. This paper introduces X2-Gait, a novel deep learning framework designed to address these challenges. X2-Gait pioneers a hierarchical, context-aware mechanism that extracts features at multiple granularities, from fine-grained joint kinematics to holistic body posture. Crucially, it designates macro-level postural features as a 'contextual anchor' to dynamically guide the interpretation of micro-level movement features via a gating network. This architecture uniquely enables dual-level interpretability, providing both a high-level postural assessment and specific, corroborating biomechanical evidence for each prediction. Evaluated on a dataset of individuals with subthreshold depression and healthy controls, X2-Gait not only achieves state-of-theart classification accuracy (70.26%) but also generates clinically meaningful, hierarchical explanations. This work represents a significant step toward developing transparent, trustworthy, and non-intrusive tools for mental health screening.

源语言英语
主期刊名Proceedings - 2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025
编辑Juan Liu, Jingshan Huang, Xiaowo Wang, Fa Zhang, Xiufen Zou, Tian Tian, Xiaohua Hu, Bin Hu, Yi Xiong
出版商Institute of Electrical and Electronics Engineers Inc.
1659-1664
页数6
ISBN(电子版)9798331515577
DOI
出版状态已出版 - 2025
已对外发布
活动2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025 - Wuhan, 中国
期限: 15 12月 202518 12月 2025

出版系列

姓名Proceedings - 2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025

会议

会议2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025
国家/地区中国
Wuhan
时期15/12/2518/12/25

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