Tris(pyrazolyl)borate Cobalt-Catalyzed Hydrogenation of C=O, C=C, and C=N Bonds: An Assistant Role of a Lewis Base

Yang Lin; De Ping Zhu; Yi Ran Du; Rui Zhang; Suo Jiang Zhang; Bao Hua Xu

doi:10.1021/acs.orglett.9b00679

Tris(pyrazolyl)borate Cobalt-Catalyzed Hydrogenation of C=O, C=C, and C=N Bonds: An Assistant Role of a Lewis Base

Yang Lin
, De Ping Zhu
, Yi Ran Du
, Rui Zhang^*
, Suo Jiang Zhang
, Bao Hua Xu

^*此作品的通讯作者

East China University of Science and Technology
Chinese Academy of Sciences
University of Chinese Academy of Sciences

科研成果: 期刊稿件 › 文章 › 同行评审

25 引用（Scopus）

摘要

The combination of tris(pyrazolyl)borate cobalt complexes and Lewis base is developed as an efficient catalyst precursor in the homogeneous hydrogenation. A broad substrate scope including carbonyls, alkenes, enamines, and imines is reduced with 60 atm of H ₂ at 60 °C. Mechanistic studies support the hydrogenation operates through a frustrated Lewis pair (FLP)-like reduction process. These results highlight the development of novel non-noble metal catalytic processes, when combined with the diverse small molecule activation chemistry associated with FLPs.

源语言	英语
页（从-至）	2693-2698
页数	6
期刊	Organic Letters
卷	21
期	8
DOI	https://doi.org/10.1021/acs.orglett.9b00679
出版状态	已出版 - 19 4月 2019
已对外发布	是

访问文件

10.1021/acs.orglett.9b00679

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{3d2c118bcb69413a9a30f67a142872f5,

title = "Tris(pyrazolyl)borate Cobalt-Catalyzed Hydrogenation of C=O, C=C, and C=N Bonds: An Assistant Role of a Lewis Base",

abstract = " The combination of tris(pyrazolyl)borate cobalt complexes and Lewis base is developed as an efficient catalyst precursor in the homogeneous hydrogenation. A broad substrate scope including carbonyls, alkenes, enamines, and imines is reduced with 60 atm of H 2 at 60 °C. Mechanistic studies support the hydrogenation operates through a frustrated Lewis pair (FLP)-like reduction process. These results highlight the development of novel non-noble metal catalytic processes, when combined with the diverse small molecule activation chemistry associated with FLPs.",

author = "Yang Lin and Zhu, \{De Ping\} and Du, \{Yi Ran\} and Rui Zhang and Zhang, \{Suo Jiang\} and Xu, \{Bao Hua\}",

note = "Publisher Copyright: Copyright {\textcopyright} 2019 American Chemical Society.",

year = "2019",

month = apr,

day = "19",

doi = "10.1021/acs.orglett.9b00679",

language = "English",

volume = "21",

pages = "2693--2698",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "8",

}

TY - JOUR

T1 - Tris(pyrazolyl)borate Cobalt-Catalyzed Hydrogenation of C=O, C=C, and C=N Bonds

T2 - An Assistant Role of a Lewis Base

AU - Lin, Yang

AU - Zhu, De Ping

AU - Du, Yi Ran

AU - Zhang, Rui

AU - Zhang, Suo Jiang

AU - Xu, Bao Hua

PY - 2019/4/19

Y1 - 2019/4/19

N2 - The combination of tris(pyrazolyl)borate cobalt complexes and Lewis base is developed as an efficient catalyst precursor in the homogeneous hydrogenation. A broad substrate scope including carbonyls, alkenes, enamines, and imines is reduced with 60 atm of H 2 at 60 °C. Mechanistic studies support the hydrogenation operates through a frustrated Lewis pair (FLP)-like reduction process. These results highlight the development of novel non-noble metal catalytic processes, when combined with the diverse small molecule activation chemistry associated with FLPs.

AB - The combination of tris(pyrazolyl)borate cobalt complexes and Lewis base is developed as an efficient catalyst precursor in the homogeneous hydrogenation. A broad substrate scope including carbonyls, alkenes, enamines, and imines is reduced with 60 atm of H 2 at 60 °C. Mechanistic studies support the hydrogenation operates through a frustrated Lewis pair (FLP)-like reduction process. These results highlight the development of novel non-noble metal catalytic processes, when combined with the diverse small molecule activation chemistry associated with FLPs.

UR - https://www.scopus.com/pages/publications/85064341887

U2 - 10.1021/acs.orglett.9b00679

DO - 10.1021/acs.orglett.9b00679

M3 - Article

C2 - 30945866

AN - SCOPUS:85064341887

SN - 1523-7060

VL - 21

SP - 2693

EP - 2698

JO - Organic Letters

JF - Organic Letters

IS - 8

ER -

Tris(pyrazolyl)borate Cobalt-Catalyzed Hydrogenation of C=O, C=C, and C=N Bonds: An Assistant Role of a Lewis Base

摘要

访问文件

其它文件与链接

学术指纹

引用此