TY - JOUR
T1 - Trimethylsilyl hydroxypropyl cellulose
T2 - Preparation, properties and as precursors to graft copolymerization of ε-caprolactone
AU - Wang, Caiqi
AU - Tan, Huimin
AU - Dong, Yuping
AU - Shao, Zhiqiang
PY - 2006/10
Y1 - 2006/10
N2 - Trimethylsilyl hydroxypropyl cellulose (TMS-HPC) was synthesized from hydroxypropyl cellulose and hexamethyldisilazane in dimethyl formamide. The structure of TMS-HPC was characterized by infrared spectroscopy, 1H NMR and 13C NMR. The obtained TMS-HPC achieved solubility in a variety of organic solvents, such as chloroform, acetone, and xylene so that the lyotropic liquid crystal mesophase can be formed in concentrated acetone. The critical concentration (C*) in acetone confirmed by PLM photographs is approximately 36%. The relationship between the structure and solubility was analyzed using XRD. With the partial protection technique of the hydroxyl group via the TMS group and the solubility of TMS-HPC in organic solvents and the easy deprotection of TMS groups, a new amphiphilic biodegradable graft poly(ε-caprolactone) (PCL) with water-soluble HPC as a backbone was obtained by homogeneous graft copolymerization. The structure of the graft copolymer (HPC-g-PCL) obtained was confirmed by 1H NMR.
AB - Trimethylsilyl hydroxypropyl cellulose (TMS-HPC) was synthesized from hydroxypropyl cellulose and hexamethyldisilazane in dimethyl formamide. The structure of TMS-HPC was characterized by infrared spectroscopy, 1H NMR and 13C NMR. The obtained TMS-HPC achieved solubility in a variety of organic solvents, such as chloroform, acetone, and xylene so that the lyotropic liquid crystal mesophase can be formed in concentrated acetone. The critical concentration (C*) in acetone confirmed by PLM photographs is approximately 36%. The relationship between the structure and solubility was analyzed using XRD. With the partial protection technique of the hydroxyl group via the TMS group and the solubility of TMS-HPC in organic solvents and the easy deprotection of TMS groups, a new amphiphilic biodegradable graft poly(ε-caprolactone) (PCL) with water-soluble HPC as a backbone was obtained by homogeneous graft copolymerization. The structure of the graft copolymer (HPC-g-PCL) obtained was confirmed by 1H NMR.
KW - Copolymer
KW - Hydroxypropyl Cellulose
KW - Substitution
KW - Trimethylsilyl Group
KW - liquid crystal
UR - https://www.scopus.com/pages/publications/33748286935
U2 - 10.1016/j.reactfunctpolym.2006.02.006
DO - 10.1016/j.reactfunctpolym.2006.02.006
M3 - Article
AN - SCOPUS:33748286935
SN - 1381-5148
VL - 66
SP - 1165
EP - 1173
JO - Reactive and Functional Polymers
JF - Reactive and Functional Polymers
IS - 10
ER -