TY - JOUR
T1 - Temporal Characteristics of Microstate Changes Representing the Neuromodulation Effect of Acupuncture at PC6 With Twirling Manipulation
AU - Wu, Jinglong
AU - Zhang, Jinyan
AU - Gao, Binbin
AU - Zhang, Zhilin
AU - Zhang, Jian
AU - Yang, Huayuan
AU - Xu, Gang
AU - Yan, Tianyi
N1 - Publisher Copyright:
© 2014 IEEE.
PY - 2026
Y1 - 2026
N2 - Acupuncture at pericardium 6 (PC6) has been clinically found to alleviate anxiety disorders and is thought to be related to regulatory effects on the autonomic nervous system, central nervous system, and default mode network. However, the relationship between the temporal characteristics of microstate changes and the related PC6 acupoints with twirling frequency manipulation remains unclear. In this study, resting-state electroencephalogram signals from 10 healthy participants were recorded at the PC6/sham acupoint with strong/weak twirling frequency manipulation. Electroencephalogram microstate analysis was conducted to obtain microstate maps and microstate parameters under different conditions. Our results showed the regulatory effects of PC6 on microstate classes C and D; the occurrence of class C was related to twirling frequency, and the duration of class D was related to acupuncture manipulation. Taken together, our findings indicate that the temporal characteristics of the microstates of classes C and D maybe essential for PC6 acupuncture with twirling frequency manipulation.
AB - Acupuncture at pericardium 6 (PC6) has been clinically found to alleviate anxiety disorders and is thought to be related to regulatory effects on the autonomic nervous system, central nervous system, and default mode network. However, the relationship between the temporal characteristics of microstate changes and the related PC6 acupoints with twirling frequency manipulation remains unclear. In this study, resting-state electroencephalogram signals from 10 healthy participants were recorded at the PC6/sham acupoint with strong/weak twirling frequency manipulation. Electroencephalogram microstate analysis was conducted to obtain microstate maps and microstate parameters under different conditions. Our results showed the regulatory effects of PC6 on microstate classes C and D; the occurrence of class C was related to twirling frequency, and the duration of class D was related to acupuncture manipulation. Taken together, our findings indicate that the temporal characteristics of the microstates of classes C and D maybe essential for PC6 acupuncture with twirling frequency manipulation.
KW - Electroencephalogram microstate
KW - pericardium 6 (PC6) acupoint
KW - resting-state networks
KW - temporal dynamics
KW - twirling frequency manipulation
UR - https://www.scopus.com/pages/publications/105012942676
U2 - 10.1109/TCSS.2025.3591517
DO - 10.1109/TCSS.2025.3591517
M3 - Article
AN - SCOPUS:105012942676
SN - 2329-924X
VL - 13
SP - 701
EP - 713
JO - IEEE Transactions on Computational Social Systems
JF - IEEE Transactions on Computational Social Systems
IS - 1
ER -