Synthesis of limettin

Si Ping Pang; Lin Wang

Synthesis of limettin

Si Ping Pang^*
, Lin Wang

^*此作品的通讯作者

材料学院

Chinese People's Liberation Army

科研成果: 期刊稿件 › 文章 › 同行评审

1 引用（Scopus）

摘要

The synthesis of limettin is studied. 5,7-dihydroxycoumarin was synthesized through phloroglucin and ethyl propionate by the catalysis of ZnCl₂, with a yield of 97.7%. 5,7-dihydroxycoumarin was reacted with methylation reagents giving limettin. The conditions of methylation reaction were studied in detail and the optimization conditions determined with a yield of 75.7%: dimethyl sulfate was used as the methylation reagent, while dimethyl sulfate and 30% NaOH solution was dropped in alternatively. The mechanism of methylation reaction is discussed.

源语言	英语
页（从-至）	743-744+752
期刊	Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology
卷	25
期	8
出版状态	已出版 - 8月 2005

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title = "Synthesis of limettin",

abstract = "The synthesis of limettin is studied. 5,7-dihydroxycoumarin was synthesized through phloroglucin and ethyl propionate by the catalysis of ZnCl2, with a yield of 97.7\%. 5,7-dihydroxycoumarin was reacted with methylation reagents giving limettin. The conditions of methylation reaction were studied in detail and the optimization conditions determined with a yield of 75.7\%: dimethyl sulfate was used as the methylation reagent, while dimethyl sulfate and 30\% NaOH solution was dropped in alternatively. The mechanism of methylation reaction is discussed.",

keywords = "Coumarin, Methylation, Synthesis",

author = "Pang, \{Si Ping\} and Lin Wang",

year = "2005",

month = aug,

language = "English",

volume = "25",

pages = "743--744+752",

journal = "Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology",

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T1 - Synthesis of limettin

AU - Pang, Si Ping

AU - Wang, Lin

PY - 2005/8

Y1 - 2005/8

N2 - The synthesis of limettin is studied. 5,7-dihydroxycoumarin was synthesized through phloroglucin and ethyl propionate by the catalysis of ZnCl2, with a yield of 97.7%. 5,7-dihydroxycoumarin was reacted with methylation reagents giving limettin. The conditions of methylation reaction were studied in detail and the optimization conditions determined with a yield of 75.7%: dimethyl sulfate was used as the methylation reagent, while dimethyl sulfate and 30% NaOH solution was dropped in alternatively. The mechanism of methylation reaction is discussed.

AB - The synthesis of limettin is studied. 5,7-dihydroxycoumarin was synthesized through phloroglucin and ethyl propionate by the catalysis of ZnCl2, with a yield of 97.7%. 5,7-dihydroxycoumarin was reacted with methylation reagents giving limettin. The conditions of methylation reaction were studied in detail and the optimization conditions determined with a yield of 75.7%: dimethyl sulfate was used as the methylation reagent, while dimethyl sulfate and 30% NaOH solution was dropped in alternatively. The mechanism of methylation reaction is discussed.

KW - Coumarin

KW - Methylation

KW - Synthesis

UR - https://www.scopus.com/pages/publications/26644468853

M3 - Article

AN - SCOPUS:26644468853

SN - 1001-0645

VL - 25

SP - 743-744+752

JO - Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology

JF - Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology

IS - 8

ER -

Synthesis of limettin

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