Synthesis of 1-amino-1, 2, 3-triazole

A preparation method of 1-amino-1, 2, 3-triazole was developed. The glyoxal bishydrazone was synthesized from glyoxal and aqueous hydrazine, and then glyoxal bishydrazone was oxidated with activated manganese dioxide to give 1-amino-1, 2, 3-triazole. The structure of 1-amino-1, 2, 3-triazole was confirmed by IR, elemental analysis, NMR and MS. Results show that 1-amino-1, 2, 3-triazole with high purity (96%) can be optimally got by crystallization from acetonitrile. The optimal amount of manganese dioxide is 2.8 N to the amount of glyoxal bishydrazone, and the reaction can be achieved within 2.5 h with the yield of 78.30%. In addition, the reaction mechanisms of decomposition and synthesis of 1-amino-1, 2, 3-triazole were discussed.