Study on properties of amphiphilic biodegradable copolymer the hydroxypropyl cellulose-graft-polycaprolactone

Cai Qi Wang; Hui Min Tan; Yu Ping Dong; Guang Tao Li

Study on properties of amphiphilic biodegradable copolymer the hydroxypropyl cellulose-graft-polycaprolactone

Cai Qi Wang^*
, Hui Min Tan
, Yu Ping Dong
, Guang Tao Li

^*此作品的通讯作者

材料学院

Tsinghua University
Beijing Institute of Technology

科研成果: 期刊稿件 › 文章 › 同行评审

1 引用（Scopus）

摘要

The properties of the amphiphilic hydroxypropyl cellulose graft polycaprolactone (HPC-g-PCL) copolymers were investigated. The results of WAXD and DSC measurements show that grafting of PCL onto HPC backbone gives rise to a very effective decrease in the crystallinity, and consequently the T_m and T_c of the graft copolymers also decrease, comparison of that of PCL homopolymer. It is also found that the lower the D_p, the lower the X_c, T_m and T_c. The hydrolysis degradation of the graft copolymers was investigated in buffer in vitro and compared with that PCL homopolymer. The degradation rates of the graft copolymers were significantly larger than that of PCL, due to decreases in the crystallinity of the PCL segment by the introduction of a hydrophilic HPC unit and its branched structure.

源语言	英语
页（从-至）	123-126
页数	4
期刊	Gaofenzi Cailiao Kexue Yu Gongcheng/Polymeric Materials Science and Engineering
卷	22
期	1
出版状态	已出版 - 1月 2006

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{58ddeacc42f44f38b3b9406d79b972de,

title = "Study on properties of amphiphilic biodegradable copolymer the hydroxypropyl cellulose-graft-polycaprolactone",

abstract = "The properties of the amphiphilic hydroxypropyl cellulose graft polycaprolactone (HPC-g-PCL) copolymers were investigated. The results of WAXD and DSC measurements show that grafting of PCL onto HPC backbone gives rise to a very effective decrease in the crystallinity, and consequently the Tm and Tc of the graft copolymers also decrease, comparison of that of PCL homopolymer. It is also found that the lower the Dp, the lower the Xc, Tm and Tc. The hydrolysis degradation of the graft copolymers was investigated in buffer in vitro and compared with that PCL homopolymer. The degradation rates of the graft copolymers were significantly larger than that of PCL, due to decreases in the crystallinity of the PCL segment by the introduction of a hydrophilic HPC unit and its branched structure.",

keywords = "Amphiphilic, Biodegradable, Caprolactone, Graft copolymers, Hydroxypropyl cellulose",

author = "Wang, \{Cai Qi\} and Tan, \{Hui Min\} and Dong, \{Yu Ping\} and Li, \{Guang Tao\}",

year = "2006",

month = jan,

language = "English",

volume = "22",

pages = "123--126",

journal = "Gaofenzi Cailiao Kexue Yu Gongcheng/Polymeric Materials Science and Engineering",

issn = "1000-7555",

publisher = "Chengdu University of Science and Technology",

number = "1",

}

TY - JOUR

T1 - Study on properties of amphiphilic biodegradable copolymer the hydroxypropyl cellulose-graft-polycaprolactone

AU - Wang, Cai Qi

AU - Tan, Hui Min

AU - Dong, Yu Ping

AU - Li, Guang Tao

PY - 2006/1

Y1 - 2006/1

N2 - The properties of the amphiphilic hydroxypropyl cellulose graft polycaprolactone (HPC-g-PCL) copolymers were investigated. The results of WAXD and DSC measurements show that grafting of PCL onto HPC backbone gives rise to a very effective decrease in the crystallinity, and consequently the Tm and Tc of the graft copolymers also decrease, comparison of that of PCL homopolymer. It is also found that the lower the Dp, the lower the Xc, Tm and Tc. The hydrolysis degradation of the graft copolymers was investigated in buffer in vitro and compared with that PCL homopolymer. The degradation rates of the graft copolymers were significantly larger than that of PCL, due to decreases in the crystallinity of the PCL segment by the introduction of a hydrophilic HPC unit and its branched structure.

AB - The properties of the amphiphilic hydroxypropyl cellulose graft polycaprolactone (HPC-g-PCL) copolymers were investigated. The results of WAXD and DSC measurements show that grafting of PCL onto HPC backbone gives rise to a very effective decrease in the crystallinity, and consequently the Tm and Tc of the graft copolymers also decrease, comparison of that of PCL homopolymer. It is also found that the lower the Dp, the lower the Xc, Tm and Tc. The hydrolysis degradation of the graft copolymers was investigated in buffer in vitro and compared with that PCL homopolymer. The degradation rates of the graft copolymers were significantly larger than that of PCL, due to decreases in the crystallinity of the PCL segment by the introduction of a hydrophilic HPC unit and its branched structure.

KW - Amphiphilic

KW - Biodegradable

KW - Caprolactone

KW - Graft copolymers

KW - Hydroxypropyl cellulose

UR - https://www.scopus.com/pages/publications/33646381353

M3 - Article

AN - SCOPUS:33646381353

SN - 1000-7555

VL - 22

SP - 123

EP - 126

JO - Gaofenzi Cailiao Kexue Yu Gongcheng/Polymeric Materials Science and Engineering

JF - Gaofenzi Cailiao Kexue Yu Gongcheng/Polymeric Materials Science and Engineering

IS - 1

ER -

Study on properties of amphiphilic biodegradable copolymer the hydroxypropyl cellulose-graft-polycaprolactone

摘要

其它文件与链接

指纹

引用此