Studies on the cyclization reaction of d-aspartic acid

Yu Chuan Li; Si Ping Pang; Yong Zhong Yu

doi:10.1016/j.cclet.2007.03.013

Studies on the cyclization reaction of d-aspartic acid

Yu Chuan Li
, Si Ping Pang^*
, Yong Zhong Yu

^*此作品的通讯作者

材料学院

Beijing Institute of Technology

科研成果: 期刊稿件 › 文章 › 同行评审

3 引用（Scopus）

摘要

The cyclization reaction of d-aspartic acid was studied, the carboxyl groups of d-aspartic acid were protected by benzyl alcohol to give compound d-dibenzyl aspartate. Then (4R)-benzyl azetidine-2-one-4-carboxylate and meso-3,6-disubstituted piperazine-2,5-diones were synthesized via intramolecular cyclization and intermolecular cyclization of d-dibenzyl aspartate, respectively, and their structures were confirmed by ¹H NMR and MS. Both cyclization reaction conditions were also investigated in detail.

源语言	英语
页（从-至）	516-518
页数	3
期刊	Chinese Chemical Letters
卷	18
期	5
DOI	https://doi.org/10.1016/j.cclet.2007.03.013
出版状态	已出版 - 5月 2007

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title = "Studies on the cyclization reaction of d-aspartic acid",

abstract = "The cyclization reaction of d-aspartic acid was studied, the carboxyl groups of d-aspartic acid were protected by benzyl alcohol to give compound d-dibenzyl aspartate. Then (4R)-benzyl azetidine-2-one-4-carboxylate and meso-3,6-disubstituted piperazine-2,5-diones were synthesized via intramolecular cyclization and intermolecular cyclization of d-dibenzyl aspartate, respectively, and their structures were confirmed by 1H NMR and MS. Both cyclization reaction conditions were also investigated in detail.",

keywords = "3,6-Disubstituted piperazine-2,5-diones, Azetidine-2-ones, Cyclization reaction, d-Aspartic acid",

author = "Li, \{Yu Chuan\} and Pang, \{Si Ping\} and Yu, \{Yong Zhong\}",

year = "2007",

month = may,

doi = "10.1016/j.cclet.2007.03.013",

language = "English",

volume = "18",

pages = "516--518",

journal = "Chinese Chemical Letters",

issn = "1001-8417",

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TY - JOUR

T1 - Studies on the cyclization reaction of d-aspartic acid

AU - Li, Yu Chuan

AU - Pang, Si Ping

AU - Yu, Yong Zhong

PY - 2007/5

Y1 - 2007/5

N2 - The cyclization reaction of d-aspartic acid was studied, the carboxyl groups of d-aspartic acid were protected by benzyl alcohol to give compound d-dibenzyl aspartate. Then (4R)-benzyl azetidine-2-one-4-carboxylate and meso-3,6-disubstituted piperazine-2,5-diones were synthesized via intramolecular cyclization and intermolecular cyclization of d-dibenzyl aspartate, respectively, and their structures were confirmed by 1H NMR and MS. Both cyclization reaction conditions were also investigated in detail.

AB - The cyclization reaction of d-aspartic acid was studied, the carboxyl groups of d-aspartic acid were protected by benzyl alcohol to give compound d-dibenzyl aspartate. Then (4R)-benzyl azetidine-2-one-4-carboxylate and meso-3,6-disubstituted piperazine-2,5-diones were synthesized via intramolecular cyclization and intermolecular cyclization of d-dibenzyl aspartate, respectively, and their structures were confirmed by 1H NMR and MS. Both cyclization reaction conditions were also investigated in detail.

KW - 3,6-Disubstituted piperazine-2,5-diones

KW - Azetidine-2-ones

KW - Cyclization reaction

KW - d-Aspartic acid

UR - https://www.scopus.com/pages/publications/34247571976

U2 - 10.1016/j.cclet.2007.03.013

DO - 10.1016/j.cclet.2007.03.013

M3 - Article

AN - SCOPUS:34247571976

SN - 1001-8417

VL - 18

SP - 516

EP - 518

JO - Chinese Chemical Letters

JF - Chinese Chemical Letters

IS - 5

ER -

Studies on the cyclization reaction of d-aspartic acid

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